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Cimaterol

VETRANAL®, analytical standard

Synonym(s):

2-Amino-5-(1-hydroxy-2-isopropylaminoethyl)benzonitrile

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About This Item

Empirical Formula (Hill Notation):
C12H17N3O
CAS Number:
Molecular Weight:
219.28
Beilstein/REAXYS Number:
2418129
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

CC(C)NCC(O)c1ccc(N)c(c1)C#N

InChI

1S/C12H17N3O/c1-8(2)15-7-12(16)9-3-4-11(14)10(5-9)6-13/h3-5,8,12,15-16H,7,14H2,1-2H3

InChI key

BUXRLJCGHZZYNE-UHFFFAOYSA-N

General description

Cimaterol is a β-adrenergic agonist.
Cimaterol is classified under the β-agonist class of drugs.

Application

Cimaterol may be used as a reference standard for the determination of the analyte in animal tissues, feeding-stuffs, and feces by high-performance liquid chromatography and post-column derivatization.
Cimaterol may be used as an analytical reference standard for the determination of the analyte in:
  • Feed samples by solid-phase extraction (SPE) and ultra-performance liquid chromatography (UPLC).
  • Pig liver, kidney and muscle samples by SPE and UPLC coupled to tandem mass spectrometry (MS/MS).
  • Bovine retina by SPE and gas chromatography-mass spectrometry (GC-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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G Van Vyncht et al.
Journal of chromatography. A, 750(1-2), 43-49 (1996-10-25)
beta-Agonists are substances used in veterinary and human medicine for the treatment of pulmonary disorders. They have found a use as growth promoters to improve meat-to-fat ratios in cattle but they are not authorized for use in the European Union.
B L Gwartney et al.
Journal of animal science, 70(7), 2144-2150 (1992-07-01)
The response time to cimaterol (CIM), a beta-adrenergic agonist, by broiler chickens for carcass characteristics, muscle composition, muscle fiber size, catheptic enzyme activity, and tenderness was determined. Two trials were conducted in which chickens were fed a control diet (CON)
A Schiavone et al.
Journal of animal physiology and animal nutrition, 88(3-4), 94-100 (2004-04-03)
Illegal dietary supplementation with beta(2)-agonists has been shown to increase protein deposition and decrease fat accretion in domestic animals. In poultry the metabolic and endocrine responses to beta(2)-agonists are not fully elucidated. In this trial the effects of dietary clenbuterol
Gas chromatography-mass spectrometry analysis of β2-agonists in bovine retina.
Hernandez-Carrasquilla M
Analytica Chimica Acta, 408(1-2), 285-290 (2000)
M Vestergaard et al.
Journal of animal science, 72(9), 2298-2306 (1994-09-01)
The objective of this study was to determine the effect of the beta-adrenergic agonist cimaterol (CIM) on fiber characteristics, capillary supply, and metabolic enzyme activities in muscles of young Friesian bulls. Four pairs of monozygotic twins in each of three

Articles

Using an Ascentis® Express F5 HPLC column, this study separates 11 β-agonists in pork by LC-MS/MS in under 8 minutes with excellent recovery and precision.

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