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Zilpaterol hydrochloride

VETRANAL®, analytical standard

Synonym(s):

(6RS,7RS)-4,5,6, 7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[ 4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O2 · HCl
CAS Number:
119520-06-8
Molecular Weight:
297.78
UNSPSC Code:
41116107
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

Storage temp.

2-8°C

InChI

1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19;/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19);1H/t11-,13-;/m1./s1

InChI key

GIEFXLLRTJNFGT-LOCPCMAASA-N

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General description

Zilpaterol belongs to the group of β-adrenergic agonists, used in the treatment of lung diseases due to its brochodilating nature. It is also widely used in veterinary medicine as a growth promoter for increasing muscle gain and decreasing fat.

Application

Zilpaterol hydrochloride analytical standard can be used as follows:
  • Determination of zilpaterol in cattle plasma and tissue samples using solid phase extraction (SPE) well plate of 96 samples for sample preparation and subsequent analysis by liquid chromatography-triple quadrupole mass spectrometry (LC-MS/MS)
  • Multi-residue analysis of 3 β-agonists, zilpaterol, clenbuterol, and ractopamine in a variety of meat samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • QuEChERS-based preparation of two types of animal tissue samples, muscle and viscera, for the analysis of seven β-agonists by liquid chromatography/tandem mass spectrometry
  • Development and validation of an LC-MS/MS method to estimate zilpaterol, ractopamine, and clenbuterol in bovine tissue samples
  • Simultaneous quantitative determination of spectinomycin, halquinol, zilpaterol, and melamine in animal feed samples by LC-MS/MS

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK4314
BCCG5268
BCCB0050
BCBW7338
BCBT9832

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J L Vipham et al.
Zoonoses and public health, 62(8), 599-608 (2015-03-18)
Despite effective food safety interventions within abattoirs, Salmonella enterica remains a common contaminant of raw ground beef. Research has recently implicated peripheral lymph nodes (PLNs) as a potential route by which Salmonella contaminates ground beef. This study examined the efficacy
A Rivera-Villegas et al.
Asian-Australasian journal of animal sciences, 32(2), 209-216 (2018-07-31)
We compare the effects of three different approved sources of supplemental zilpaterol on growth-performance responses and carcass characteristics of finishing lambs. Twenty four Pelibuey×Katahdin lambs (46.75±2.43 kg) were used in a 33-day feeding trial. Lambs were fed a dry rolled
J A Hagenmaier et al.
Journal of animal science, 94(12), 5064-5076 (2017-01-04)
Feedlot cattle ( = 1,395; BW = 568 ± 43 kg) were used to evaluate the effects of shade on animal welfare, growth performance, and carcass quality during the summer of 2013 in a Kansas commercial feedlot. Seven lots of
Ennet Moholisa et al.
Journal of the science of food and agriculture, 97(8), 2375-2381 (2016-10-08)
Animal age as determined by number of permanent incisors (p. i.) is used in classification of beef carcasses to describe expected meat tenderness. However, animals differing in age are reared under different production systems (pasture or feedlot). In addition to
Weilin L Shelver et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 35(8), 1519-1529 (2018-04-13)
Zilpaterol is a β-adrenergic agonist feed additive approved in the United States to increase weight gain and improve feed efficiency of cattle. A zilpaterol immunochromatographic assay was developed as an economical and user-friendly rapid detection method for zilpaterol and validated
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