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33034

Sigma-Aldrich

L-Ascorbic acid

puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

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Synonym(s):
L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

ACS reagent
puriss. p.a.

agency

Ph. Eur.
USP/NF
reag. ISO

assay

99.7-100.5% (oxidimetric)

form

solid

optical activity

[α]20/D +20.5 to +21.5°, c = 10% in H2O

technique(s)

IR spectroscopy: suitable

impurities

related substances, in accordance (HPLC)
≤0.001% heavy metals (by ICP-OES)

ign. residue

≤0.05% (as SO4)

loss

≤0.1% loss on drying, 105 °C

pH

2.1-2.6 (20 °C, 5%)

mp

190-192 °C ((decomp)) (lit.)
190-194 °C (dec.)

solubility

water: soluble 176 g/L at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤20 mg/kg

cation traces

As: ≤1 mg/kg
Cu: ≤5 mg/kg
Fe: ≤2 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

suitability

complies for appearance of solution
passes test for identity (IR)

application(s)

cell analysis

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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This Item
795437A0278A5960
L-Ascorbic acid puriss. p.a., ACS reagent, reag. ISO, Ph. Eur., 99.7-100.5% (oxidimetric)

33034

L-Ascorbic acid

-
L-Ascorbic acid anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99%

795437

L-Ascorbic acid

-
L-Ascorbic acid reagent grade

A0278

L-Ascorbic acid

Essential Grade
L-Ascorbic acid BioXtra, ≥99.0%, crystalline

A5960

L-Ascorbic acid

Premium Grade
suitability

complies for appearance of solution, passes test for identity (IR)

suitability

-

suitability

-

suitability

-

technique(s)

IR spectroscopy: suitable

technique(s)

-

technique(s)

HPLC: suitable

technique(s)

cell culture | mammalian: suitable

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic

biological source

-

assay

99.7-100.5% (oxidimetric)

assay

≥99%

assay

≥98% (with Iodine, titration)

assay

≥99.0%

form

solid

form

crystals or granules, powder or chunks

form

powder

form

crystalline

General description

L-Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. Benefits of vitamin C may include protection against immune system deficiencies, cardiovascular disease, hyperpigmentation, skin protection, anti-aging, iron absorption, and red blood cell production. It is also useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Application

L-Ascorbic acid has been used as an analytical interfering substance in glycated albumin (GA) enzymatic assay.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Testa R, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 1(2), 162-171 (2016)
Total phenols, ascorbic acid, β-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities.
Barros L, et al.
Food Chemistry, 103(2), 413-419 (2007)
A family of mammalian NaI[plus]I-dependent L-ascorbic acid transporters.
Tsukaguchi H, et al.
Nature, 673(1), 70-75 (1999)
T R Tickner et al.
Clinica chimica acta; international journal of clinical chemistry, 85(2), 125-129 (1978-04-17)
A new colorimetric method for the assay of biliverdin in biological fluids is described. The method, based upon the reaction of biliverdin with barbituric acid, offers improved sensitivity and selectivity when compared to direct spectrophotometric measurements. Using this method biliverdinaemia
Jiali Zhang et al.
Chemical communications (Cambridge, England), 46(7), 1112-1114 (2010-02-04)
We demonstrated that the individual graphene oxide sheets can be readily reduced under a mild condition using L-ascorbic acid (L-AA). This simple approach should find practical applications in large scale production of water soluble graphene.

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