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A1300000

Ascorbic acid

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
L-Ascorbic acid, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP Reference standard

API family

ascorbic acid

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

190-194 °C (dec.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

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1 of 4

This Item
1043003PHR1008BP461
Ascorbic acid European Pharmacopoeia (EP) Reference Standard

A1300000

Ascorbic acid

Ascorbic acid United States Pharmacopeia (USP) Reference Standard

1043003

Ascorbic acid

Ascorbic Acid Pharmaceutical Secondary Standard; Certified Reference Material

PHR1008

Ascorbic Acid

Ascorbic acid British Pharmacopoeia (BP) Reference Standard

BP461

Ascorbic acid

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

format

neat

format

neat

format

neat

format

neat

form

solid

form

-

form

solid

form

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ascorbic EP reference standard, intended for use only as specifically prescribed in the European Pharmacopoeia. Also used for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Reversed-phase ion-pair HPLC determination of some water-soluble vitamins in pharmaceuticals
Ivanovic D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 18(6), 999-1004 (1999)
Ascorbic acid
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 18(6), 6868-6869 (2019)
Spectrophotometric determination of L-ascorbic acid in pharmaceuticals
Szpikowska-Sroka B and Poledniok J
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