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33347

Supelco

AOZ

VETRANAL®, analytical standard

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Synonym(s):
3-Amino-2-oxazolidinone, NSC 111187, NSC 196570, NSC 38250
Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
Molecular Weight:
102.09
Beilstein/REAXYS Number:
109430
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

63-69 °C

suitability

passes test for identity

application(s)

clinical testing

format

neat

SMILES string

NN1CCOC1=O

InChI

1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2

InChI key

KYCJNIUHWNJNCT-UHFFFAOYSA-N

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This Item
338803386833349
AOZ VETRANAL®, analytical standard

33347

AOZ

AOZ-d4 VETRANAL®, analytical standard

33880

AOZ-d4

2-NP-AOZ VETRANAL®, analytical standard

33868

2-NP-AOZ

AMOZ VETRANAL®, analytical standard

33349

AMOZ

application(s)

clinical testing

application(s)

clinical testing

application(s)

clinical testing

application(s)

clinical testing

format

neat

format

neat

format

neat

format

neat

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

analytical standard

grade

analytical standard

grade

analytical standard

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

General description

AOZ, also known as 3-amino-2-oxazolidinone, is a metabolite of the synthetic nitrofuran veterinary antibiotic ― furazolidone.

Application

The analytical standard can be used as follows:
  • Development of an electrochemical impedimetric immunosensor based on immobilization of a monoclonal antibody on a gold electrode, to determine AOZ in six food samples
  • Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry
  • Detection and measurement of AOZ in tissue samples obtained from four animals by immunochromatography test stripes based on colloidal gold-monoclonal antibody
  • LC-MS/MS analysis of nitrofuran and nitroimidazole metabolite residues in honey samples after their extraction by a modified QuEChERS-based method
  • Screening of nitrofuran metabolite residues from shrimp muscle samples by an HPLC method combined with diode array detection

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Quan Wang et al.
Analytical and bioanalytical chemistry, 410(1), 223-233 (2017-11-01)
There is an urgent need for the rapid and simultaneous detection of multiple analytes present in a sample matrix. Here, a multiplex immunochromatographic test (multi-ICT) was developed that successfully allowed for the rapid and simultaneous detection of four major nitrofuran
Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation
Diblikova I, et al.
Analytica Chimica Acta, 540, 285-292 (2005)
Jinyan Gong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1146, 122018-122018 (2020-04-26)
This study established a validated analytical method for the first time on the determination of nitrofuran metabolites, including semicarbazide (SEM), 1-aminohydantoin (AHD), 3-amino-2-oxazolidinone (AOZ) and 3-amino-5-morpholinomethyl-2-oxazolinone (AMOZ) in gelatin Chinese medicine. A C18 column with the mobile phase consisting of
Kangkang Wang et al.
ACS omega, 5(30), 18887-18893 (2020-08-11)
Nitrofuran (NF) is a class of broad-spectrum antibiotics that are used illegally in animal feeding. NF and its metabolites have proven to pose potential risk to human health. To address the current analytical needs to quantify low levels of NF
Pierre Guichard et al.
Food chemistry, 342, 128389-128389 (2020-12-04)
LC-MS/MS method for confirmation of nitrofuran metabolites in meat and aquaculture products, including the nifursol metabolite (DNSH), was developed. The nitrofuran metabolites investigated were as follows: 3-amino-2-oxazolidinone (AOZ), 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), 1-aminohydantoine (AHD), semicarbazide (SEM) and 3,5-dinitrosalicylic acid hydrazide (DNSH). The

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