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33880

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AOZ-d4

VETRANAL®, analytical standard

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Synonym(s):
3-Aminooxazolidin-2-one-d4, 4,4,5,5-Tetradeutero-3-amino-oxazolidin-2-one
Empirical Formula (Hill Notation):
C3H2D4N2O2
CAS Number:
Molecular Weight:
106.12
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

mass shift

M+4

SMILES string

[2H]C1([2H])OC(=O)N(N)C1([2H])[2H]

InChI

1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2/i1D2,2D2

InChI key

KYCJNIUHWNJNCT-LNLMKGTHSA-N

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AOZ-d4 VETRANAL®, analytical standard

33880

AOZ-d4

AOZ VETRANAL®, analytical standard

33347

AOZ

AMOZ-d5 VETRANAL®, analytical standard

33881

AMOZ-d5

AMOZ VETRANAL®, analytical standard

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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

analytical standard

grade

analytical standard

grade

analytical standard

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

product line

VETRANAL®

product line

VETRANAL®

product line

VETRANAL®

product line

VETRANAL®

General description

It is an isotopically labelled solution of AOZ, also known as 3-amino-2-oxazolidinone, a metabolite of the synthetic nitrofuran veterinary antibiotic― furazolidone.

Application

The analytical standard can be used as an internal standard for the following:
  • Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry (MS/MS)
  • Determination of four nitrofuran metabolites in a variety of food samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) following their extraction using a solid-phase microextraction (SPME) probe
  • Simultaneous estimation of nitrofuran and chloramphenicol residues in animal-based food products using UHPLC, coupled with high-resolution mass spectrometry (HRMS)
  • Development of a UHPLC-MS/MS-based method for the estimation of nitrofurans along with their metabolites in biological samples
  • Liquid-liquid extraction of chloramphenicol, florfenicol, and nitrofuran metabolites from honey samples for their analysis by LC-MS/MS
  • Estimation of nitrofuran metabolites in poultry muscle and eggs using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Determination of nitrofuran metabolites in poultry muscle and eggs by liquid chromatography-tandem mass spectrometry
Finzi KJ, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 824(1-2), 30-35 (2005)
Analysis of nitrofuran metabolic residues in salt by liquid chromatography--tandem mass spectrometry
Pereira S.A, et al.
Analytica Chimica Acta, 514(1), 9-13 (2004)
EunChae Ryu et al.
Environmental science and pollution research international, 28(6), 7551-7563 (2020-10-11)
A simplified method is described for reducing the analysis time of nitrofurans (NFs) and nitrofuran metabolites (NFMs) in the aquatic animals. Most existing HPLC-MS/MS methods are intended only for NFMs and are based on their fast metabolic transformations. We optimized

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