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34029

Supelco

Aflatoxin B1 solution

2 μg/mL in acetonitrile, analytical standard

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Empirical Formula (Hill Notation):
C17H12O6
CAS Number:
Molecular Weight:
312.27
Beilstein/REAXYS Number:
1269174
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

concentration

2 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

[H][C@]12OC=C[C@@]1([H])c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1

InChI key

OQIQSTLJSLGHID-WNWIJWBNSA-N

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This Item
CRM46323CRM44647A6636
Aflatoxin B1 solution 2 μg/mL in acetonitrile, analytical standard

34029

Aflatoxin B1 solution

Aflatoxin B1 solution certified reference material, 3 μg/mL in benzene:acetonitrile (98:2), ampule of 1 mL

CRM46323

Aflatoxin B1 solution

Aflatoxin B1 solution certified reference material, 20 μg/mL in methanol, ampule of 1 mL

CRM44647

Aflatoxin B1 solution

grade

analytical standard

grade

certified reference material, TraceCERT®

grade

certified reference material, TraceCERT®

grade

-

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

-

format

single component solution

format

single component solution

format

single component solution

format

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

concentration

2 μg/mL in acetonitrile

concentration

3 μg/mL in benzene:acetonitrile (98:2)

concentration

20 μg/mL in methanol

concentration

-

General description

Aflatoxin B1 is a mycotoxin found to be hepatocarcinogenic in nature. It has a strong affinity for the deoxyribonucleic acid (DNA) and binds to both native and denatured deoxyribonucleic acid (DNA) as indicated by spectroscopy and equilibrium dialysis results. This fungal metabolic product is commonly found in food and feed, contaminated by Aspergillus species.

The product is supplied in CERTAN® vial.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Aflatoxin B1 solution may be used as an analytical reference standard for the determination of the analyte in meat, meat products, eggs and milk using high-performance liquid chromatography (HPLC) with fluorescence and ultraviolet detection.

Legal Information

CERTAN is a registered trademark of LGC Group

related product

Product No.
Description
Pricing

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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25G
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Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1.
McGlynn AK, et al.
Proceedings of the National Academy of Sciences of the USA, 92(6), 2384-2387 (1995)
Anna Z Wec et al.
Cell host & microbe, 25(1), 39-48 (2019-01-11)
Passive administration of monoclonal antibodies (mAbs) is a promising therapeutic approach for Ebola virus disease (EVD). However, all mAbs and mAb cocktails that have entered clinical development are specific for a single member of the Ebolavirus genus, Ebola virus (EBOV)
Aflatoxin B1 induces the transversion of G-> T in codon 249 of the p53 tumor suppressor gene in human hepatocytes.
Aguilar F, et al.
Proceedings of the National Academy of Sciences of the USA, 90(18), 8586-8590 (1993)
M B Sporn et al.
Science (New York, N.Y.), 151(3717), 1539-1541 (1966-03-25)
Aflatoxin B(1) binds to both native and denatured DNA, as shown by spectroscopy and equilibrium dialysis. It also strongly inhibits incorporation of cytidine into rat liver nuclear RNA and lowers the RNA content of the nucleus. The extremle toxicity and
Determination of aflatoxins in eggs, milk, meat and meat products using HPLC fluorescent and UV detectors.
Herzallah MS.
Food Chemistry, 114(3), 1141-1146 (2009)

Protocols

LC/MS/MS Analysis of Aflatoxins in Hops on Ascentis® Express 2.7 μm Phenyl-Hexyl after Cleanup Using Supel™ Tox AflaZea SPE

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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