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34127

Supelco

Patulin solution

100 μg/mL in acetonitrile, analytical standard

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Synonym(s):
4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one, PAT
Empirical Formula (Hill Notation):
C7H6O4
CAS Number:
Molecular Weight:
154.12
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

OC1OCC=C2OC(=O)C=C12

InChI

1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

InChI key

ZRWPUFFVAOMMNM-UHFFFAOYSA-N

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34127

Patulin solution

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35410

Citrinin solution

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3-Acetyldeoxynivalenol solution

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

format

single component solution

format

single component solution

format

single component solution

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

concentration

100 μg/mL in chloroform

concentration

~100 μg/mL in acetonitrile

concentration

~100 μg/mL in acetonitrile

General description

Patulin is an important mycotoxin produced by several species of mold, especially within PenicilliumAspergillus and Byssochlamys. It is commonly found in fruits especially apples, pears and grapes.
Patulin is a mycotoxin produced by several mold species. It has been found in fruit, especially apples, fruit juice, cider and stewed fruits. Because of its highly toxic properties, this compound has been the focus of many studies.

Application

Patulin solution may be used as an analytical reference standard for the determination of the analyte in:
  • dried apple rings using high-performance liquid chromatography with diode array detection (HPLC-DAD)(1)
  • fruit juices using high-performance liquid chromatography with diode array detection (HPLC-DAD) and gas chromatography coupled to mass spectrometry (GC-MS)(2)

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

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T1503
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25G
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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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HPLC-DAD method for the determination of patulin in dried apple rings.
Katerere RD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 19(4), 389-392 (2008)
Eszter Horváth et al.
Acta biologica Hungarica, 63(3), 389-398 (2012-09-12)
The effects of the mycotoxin patulin on the thermodynamics and kinetics of the transition of bovine serum albumin (BSA) in aqueous solution were studied by Differential Scanning Calorimetry and Photoluminescence methods. Results show that in the presence of patulin, the
Marieke Vansteelandt et al.
Fungal biology, 116(9), 954-961 (2012-09-08)
Genus Penicillium represents an important fungal group regarding to its mycotoxin production. Secondary metabolomes of eight marine-derived strains belonging to subgenera Furcatum and Penicillium were investigated using dereplication by liquid chromatography (LC)-Diode Array Detector (DAD)-mass spectrometry (MS)/MS. Each strain was
S Hatab et al.
Journal of applied microbiology, 112(5), 892-899 (2012-03-08)
Apples and apple products are the most notably commodities contaminated with patulin (PAT), which cause detrimental effects on human health and economic problems. The primary objective of this study was to investigate the removal of PAT contamination from apple juice
Assunta Raiola et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3068-3072 (2012-06-13)
Apple juices and purees represent categories widely consumed by whole population and above all children. Patulin (PAT) is a mycotoxin known for its acute and chronic effects in animals. Several studies indicate there is a risk associated to the PAT

Protocols

This selective and fast MIP extraction procedure allows trace amounts of patulin to be easily detected in apple juice, with high analyte recovery and reproducibility.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service