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48917-U

Sigma-Aldrich

ProClin™ 300

ProClin™ preservative for use in IVD manufacturing, pkg of 3.6 L, CMIT/MIT 3 %

Synonym(s):

3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.21

Quality Level

300

form

liquid

shelf life

3 yr

contains

Alkyl Carboxylate

composition

CMIT/MIT, 3%

packaging

pkg of 3.6 L

parameter

<45 °C operating temperature

color

colorless to light yellow

matrix

Modified glycol

operating pH range

2.5-8.5

pH

4.1 (100 g/L)

bp

189 °C

mp

-40 °C

solubility

water: soluble

density

1.03 g/cm3

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Application

ProClin™ preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin™ highly efficient even over extended storage periods of your IVD components.

Legal Information

ProClin is a trademark of LANXESS Corp.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

244.4 °F - closed cup

flash_point_c

118 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV4372
MKCW1837
MKCV6710
MKCT2080
MKCT1903

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James P Higham et al.
PloS one, 6(7), e22398-e22398 (2011-07-30)
Nutritional status is a critical element of many aspects of animal ecology, but has proven difficult to measure non-invasively in studies of free-ranging animals. Urinary C-peptide of insulin (UCP), a small polypeptide cleaved in an equimolar ratio from proinsulin when

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