49761

Spermidine

analytical standard

• Synonym(s): 1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane
• Linear Formula: NH₂(CH₂)₃NH(CH₂)₄NH₂
• CAS Number: 124-20-9
• Molecular Weight: 145.25
• Beilstein/REAXYS Number: 1698591
• EC Number: 204-689-0
• MDL number: MFCD00008229
• UNSPSC Code: 85151701
• PubChem Substance ID: 329757521
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥97.5% (NT); ≥99.0% (GC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.479 (lit.)
• density: 0.925 g/mL at 25 °C (lit.)
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• storage temp.: 2-8°C
• SMILES string: NCCCCNCCCN
• InChI: 1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
• InChI key: ATHGHQPFGPMSJY-UHFFFAOYSA-N

Description

General description

Spermidine is a naturally occurring polyamine compound commonly found in food. It is essential for cell growth and survival.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Spermidine may be used as one of the reference standard for the determination of spermidine in biological samples by high performance liquid chromatography-electrospray ionization–ion trap tandem mass spectrometry (HPLC–ESI–ITMS/MS).

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Caution

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 233.6 °F - closed cup
• flash_point_c: 112 °C - closed cup