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49909

Sigma-Aldrich

Lanolin

tested according to Ph. Eur.

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Synonym(s):
Adeps lanae, Wool fat
CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

agency

USP/NF
tested according to Ph. Eur.

Quality Level

autoignition temp.

833 °F

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This Item
W30351813568801356905
vibrant-m

49909

Lanolin

vibrant-m

W303518

Stearic acid

vibrant-m

1356880

Lanolin

vibrant-m

1356905

Lanolin alcohols

agency

USP/NF

agency

-

agency

-

agency

-

autoignition temp.

833 °F

autoignition temp.

-

autoignition temp.

833 °F

autoignition temp.

-

General description

Lanolin is a wool fat. It is a semisolid of high viscosity. Contact allergy to lanolin (wool alcohols), an important sensitizer, in a central London teaching hospital patch-test population has been reported. Simplified extraction of organochlorine and organophosphorus pesticides, frequently found in lanolin, has been proposed. It is utilized as an emulsifier in pharmaceutical and cosmetic formulations.

Application

Lanolin was used to compose the lanolin ointment to estimate the release kinetics of izotretinon and heparin from various semisolid dosage forms by UV-VIS spectroscopy. It was used to prepare the emulsified aqueous solutions containing crystalline dicarboxylic acid. It may be added as excipient to compose a nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


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S H Wakelin et al.
The British journal of dermatology, 145(1), 28-31 (2001-07-17)
Lanolin is often stated to be an important sensitizer but some of the available literature is based on the analysis of high-risk patients. To analyse the frequency of contact allergy to lanolin (wool alcohols) in a central London teaching hospital
Oxalic acid as a heterogeneous ice nucleus in the upper troposphere and its indirect aerosol effect.
Zobrist B, et al.
Atmospheric Chemistry and Physics, 6(10), 3115-3129 (2006)
H Diserens
Journal - Association of Official Analytical Chemists, 72(6), 991-993 (1989-11-01)
In the proposed method, a light petroleum solution of lanolin (wool fat) is adsorbed on diatomaceous earth in an Extrelut column, and the pesticides are eluted with acetonitrile saturated with light petroleum. After evaporation to a small volume, the extract
Flora B de Waard-van der Spek et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 26(7), 598-606 (2015-08-20)
Allergic contact dermatitis (ACD) in children appears to be on the increase, and contact sensitization may already begin in infancy. The diagnosis of contact dermatitis requires a careful evaluation of a patient's clinical history, physical examination, and skin testing. Patch
Wenjian Zhang et al.
Nanotechnology, 25(12), 125101-125101 (2014-02-28)
A novel nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye has been successfully developed. The excipients used as semisolid lipids were petrolatum and lanolin, as used in conventional eye ointment, which were coupled with medium-chain triglycerides

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