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50202

Supelco

Tetrahydrocurcumin

analytical standard

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Synonym(s):
1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione
Empirical Formula (Hill Notation):
C21H24O6
CAS Number:
Molecular Weight:
372.41
Beilstein/REAXYS Number:
3485469
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O

InChI

1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3

InChI key

LBTVHXHERHESKG-UHFFFAOYSA-N

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This Item
SMB00370C772769727
Tetrahydrocurcumin analytical standard

50202

Tetrahydrocurcumin

Tetrahydrocurcumin ≥96% (HPLC)

SMB00370

Tetrahydrocurcumin

Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

C7727

Curcumin

Hexahydrocurcumin analytical standard

69727

Hexahydrocurcumin

format

neat

format

-

format

-

format

neat

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

grade

analytical standard

grade

-

grade

-

grade

analytical standard

assay

≥95.0% (HPLC)

assay

≥96% (HPLC)

assay

≥80% (Curcumin), ≥94% (curcuminoid content)

assay

≥90.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the label

General description

Tetrahydrocurcumin is a colorless compound and a major metabolite of curcumin, which is known to possess antioxidant activity and inhibitory effects on tertiary butyl hydroperoxide-induced lipid peroxidation. It can be obtained via hydrogenation of curcumin in the presence of platinum(IV)oxide.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

385.2 °F

flash_point_c

196.2 °C


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Curcumin ≥94% (curcuminoid content), ≥80% (Curcumin)

Sigma-Aldrich

C7727

Curcumin

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Sigma-Aldrich

8.20354

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Palladium on carbon extent of labeling: 10 wt. % loading, matrix carbon, dry support

Sigma-Aldrich

520888

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Demethoxycurcumin analytical standard

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78246

Curcumin

1,4-Dioxane-d8 ≥99 atom % D

Sigma-Aldrich

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1,4-Dioxane-d8

Ching-Shu Lai et al.
Molecular nutrition & food research, 55(12), 1819-1828 (2011-09-03)
Tetrahydrocurcumin (THC), a major metabolite of curcumin (CUR), has been demonstrated to be anti-cancerogenic and anti-angiogenic and prevents type II diabetes. In this present study, we investigated the chemopreventive effects and underlying molecular mechanisms of dietary administration of CUR and
Pravit Asawanonda et al.
Photomedicine and laser surgery, 28(5), 679-684 (2010-10-22)
The aim of this study was to compare the efficacy of targeted narrowband UVB phototherapy plus topical tetrahydrocurcuminoid with that of targeted narrowband UVB monotherapy for induction of repigmentation in vitiligo. The 308-nm excimer laser and targeted narrowband UVB phototherapy
Symone M San Miguel et al.
Archives of oral biology, 56(8), 812-822 (2011-04-05)
Antioxidants (AOs) are the first line of defence against free radical damage and are critical for maintaining optimum health and well being. The need for AOs becomes even more critical with increased exposure to free radicals generated by pollution, cigarette
Kei Shimoda et al.
Natural product communications, 7(4), 529-530 (2012-05-12)
Cultured plant cells of Marchantia polymorpha, Nicotiana tabacum, Phytolacca americana, Catharanthus roseus, and Gossypium hirsutum were examined for their ability to reduce curcumin. Only M. polymorpha cells converted curcumin into tetrahydrocurcumin in 90% yield in one day. Time-course experiment revealed
Saowanee Nakmareong et al.
Naunyn-Schmiedeberg's archives of pharmacology, 383(5), 519-529 (2011-03-31)
Inhibition of nitric oxide synthesis with N ( ω )-nitro-L-arginine methyl ester (L-NAME) induces marked hypertension and oxidative stress. Curcumin (CUR) has been shown strong antioxidant property. Tetrahydrocurcumin (THU), a major metabolite of CUR, possesses several pharmacological effects similar to

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