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Supelco

Myristic acid

analytical standard

Synonym(s):

1-Tridecanecarboxylic acid, C14:0, NSC 5028, Tetradecanoic acid

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About This Item

Linear Formula:
CH3(CH2)12COOH
CAS Number:
Molecular Weight:
228.37
Beilstein/REAXYS Number:
508624
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

assay

≥99.5% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

250 °C/100 mmHg (lit.)

mp

52-54 °C (lit.)
53-56 °C

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

CCCCCCCCCCCCCC(O)=O

InChI

1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)

InChI key

TUNFSRHWOTWDNC-UHFFFAOYSA-N

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General description

Myristic acid is an important bioactive component of Suanzaoren seed, which is one of the most commonly used Chinese medicine with therapeutic properties such as hypotensive, antihypoxia, hypnotic-sedative, antihyperlipidemia, and hypothermic effects.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

Myristic acid may be used as an analytical reference standard for the quantification of the anayte in Ziziphus jujuba using high performance liquid chromatography with evaporative light scattering detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Binding to serum albumin

Storage Class

11 - Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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A O Pedersen et al.
The Journal of biological chemistry, 263(21), 10236-10239 (1988-07-25)
Dialysis rate determinations of several fatty acids in the absence of albumin revealed that the myristate anion, like that of laurate, in aqueous solution, pH 7.5, is present as a monomer anion when the concentration is below 25 microM. Palmitate
Simultaneous determination of saponins and fatty acids in Ziziphus jujuba (Suanzaoren) by high performance liquid chromatography-evaporative light scattering detection and pressurized liquid extraction
Zhao.J, et al.
Journal of Chromatography A, 1108(2), 188-194 (2006)
Dalit Shental-Bechor et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(44), 17839-17844 (2012-08-01)
We present an integrated experimental and computational study of the molecular mechanisms by which myristoylation affects protein folding and function, which has been little characterized to date. Myristoylation, the covalent linkage of a hydrophobic C14 fatty acyl chain to the
Sarah Brice Russo et al.
The Journal of clinical investigation, 122(11), 3919-3930 (2012-10-02)
Diabetic cardiomyopathy (DbCM), which consists of cardiac hypertrophy and failure in the absence of traditional risk factors, is a major contributor to increased heart failure risk in type 2 diabetes patients. In rodent models of DbCM, cardiac hypertrophy and dysfunction
Nikolay Burnaevskiy et al.
Nature, 496(7443), 106-109 (2013-03-29)
Protein N-myristoylation is a 14-carbon fatty-acid modification that is conserved across eukaryotic species and occurs on nearly 1% of the cellular proteome. The ability of the myristoyl group to facilitate dynamic protein-protein and protein-membrane interactions (known as the myristoyl switch)

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