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78666

Supelco

Taxifolin

analytical standard

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Synonym(s):
(2R,3R)-3,3′,4′,5,7-Pentahydroxyflavanone, (2R,3R)-Dihydroquercetin
Empirical Formula (Hill Notation):
C15H12O7
CAS Number:
Molecular Weight:
304.25
Beilstein/REAXYS Number:
5299277
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥85% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3

InChI

1S/C15H12O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,14-19,21H/t14-,15+/m0/s1

InChI key

CXQWRCVTCMQVQX-LSDHHAIUSA-N

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1 of 4

This Item
PHL892844225116654
vibrant-m

78666

Taxifolin

vibrant-m

PHL89284

(+)-Taxifolin

vibrant-m

42251

Apigenin

vibrant-m

16654

Quercetin 3-glucoside

application(s)

food and beverages

application(s)

-

application(s)

food and beverages

application(s)

food and beverages

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

assay

≥85% (HPLC)

assay

≥95.0% (HPLC)

assay

≥99% (HPLC)

assay

≥98% (HPLC)

grade

analytical standard

grade

primary reference standard

grade

analytical standard

grade

analytical standard

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

General description

Taxifolin is a plant flavonoid, which may find applications in the treatment of coronary heart disease, angina pectoris, cerebral thrombosis, cerebral infarction and sequelae.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Taxifolin can be used as a reference standard for the determination of taxifolin in plasma of rabbit using high performance liquid chromatography technique(HPLC).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

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T1503
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25G
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705578-5MG-PW

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MMYOMAG-74K-13

1000309185

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Determination and pharmacokinetic study of taxifolin in rabbit plasma by high-performance liquid chromatography
Pozharitskaya.NO, et al.
Phytomedicine, 16, 244-251 (2009)
Modulation of hepatic lipoprotein synthesis and secretion by taxifolin, a plant flavonoid
Theriault A, et al.
Journal of Lipid Research, 41, 1969-1979 (2000)
Naomi Oi et al.
Cancer prevention research (Philadelphia, Pa.), 5(9), 1103-1114 (2012-07-19)
Skin cancer is one of the most commonly diagnosed cancers in the United States. Taxifolin reportedly exerts multiple biologic effects, but the molecular mechanisms and direct target(s) of taxifolin in skin cancer chemoprevention are still unknown. In silico computer screening
Mijun Peng et al.
Environmental toxicology and pharmacology, 33(2), 327-333 (2012-02-04)
The effect of heavy metal ions, Cd(2+), Hg(2+) and Pb(2+) on taxifolin binding to bovine serum albumin (BSA) has been investigated by spectroscopic methods. The results indicated that the presence of heavy metal ions significantly affected the binding modes and
Anita Elaine Weidmann
European journal of pharmacology, 684(1-3), 19-26 (2012-04-20)
Dihydroquercetin (taxifolin) is a potent flavonoid found in onions, French maritime bark, milk thistle, tamarind seeds and commercially available semi-synthetic monoHER marketed as Venoruton. This review focuses on the therapeutic promise of dihydroquercetin in major disease states such as cancer

Articles

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