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Sulfamic acid

analytical standard (for acidimetry), ACS reagent

Synonym(s):

Aminosulfonic acid, Sulphamic acid, Amidosulfonic acid

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About This Item

Linear Formula:
NH2SO3H
CAS Number:
Molecular Weight:
97.09
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

grade

ACS reagent
analytical standard (for acidimetry)

Quality Level

agency

complies with DIN 19266

assay

99.3-100.3% (dried material)

mp

215-225 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤10 mg/kg
sulfate (SO42-): ≤500 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤10 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

application(s)

environmental
food and beverages
general analytical
industrial qc
pharmaceutical

format

mixture

SMILES string

NS(O)(=O)=O

InChI

1S/H3NO3S/c1-5(2,3)4/h(H3,1,2,3,4)

InChI key

IIACRCGMVDHOTQ-UHFFFAOYSA-N

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General description

Sulfamic acid, a strong inorganic acid, exists in crystalline form. It is stable, non-hygroscopic, odorless, and colorless in dry state, making its commercial packaging and handling convenient.

Application

It can be used as an acidimetric standard for analytical applications.
Sulfamic acid also finds its use as a primary standard in non-aqueous visual, conductometric, and potentiometric titrations.

Features and Benefits

  • Available in a secure glass bottle to ensure its stability for the entire shelf life until opened.
  • High-quality offering accurate titer determinations
  • Accompanied by a detailed certificate of analysis (CoA)

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Certificates of Analysis (COA)

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Laszlo Tarko et al.
Bioorganic & medicinal chemistry, 21(6), 1404-1409 (2012-12-05)
The last version of the PRECLAV algorithm was used to investigate a series of sulfamate/sulfamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. PRECLAV allows identification of outliers for lead hopping, significant molecular fragments and similarity computation of a calibration set vs.
Liana Hie et al.
Organic letters, 14(16), 4182-4185 (2012-08-02)
A facile nickel-catalyzed method to achieve the amination of synthetically useful aryl sulfamates and carbamates is reported. Contrary to most Ni-catalyzed amination reactions, this user-friendly approach relies on an air-stable Ni(II) precatalyst, which, when employed with a mild reducing agent
Derek J Langeslay et al.
Glycobiology, 22(9), 1173-1182 (2012-05-18)
Sulfamate groups (NHSO(3)(-)) are important structural elements in the glycosaminoglycans (GAGs) heparin and heparan sulfate (HS). In this work, proton nuclear magnetic resonance (NMR) line-shape analysis is used to explore the solvent exchange properties of the sulfamate NH groups within
Keisuke Takahashi et al.
Organic letters, 14(6), 1644-1647 (2012-03-07)
A total synthesis of (-)-kaitocephalin, an ionotropic glutamate receptor antagonist, is accomplished in highly stereocontrolled manner via Overman rearrangement, rhodium-catalyzed benzylic C-H amination, pyrrolidine formation involving nucleophilic opening of a cyclic sulfamate, and rhodium-catalyzed allylic C-H amination as key steps.
Marie Lopez et al.
Journal of the American Chemical Society, 133(45), 18452-18462 (2011-10-01)
Carbonic anhydrases (CAs) are enzymes whose endogenous reaction is the reversible hydration of CO(2) to give HCO(3)(-) and a proton. CA are also known to exhibit weak and promiscuous esterase activity toward activated esters. Here, we report a series of

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