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91312

Sigma-Aldrich

(R)-(−)-Phenylephrine hydrochloride

tested according to Ph. Eur.

Synonym(s):

Phenylephrini hydrochloridum, (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride

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About This Item

Linear Formula:
HOC6H4CH(CH2NHCH3)OH·HCl
CAS Number:
61-76-7
Molecular Weight:
203.67
Beilstein/REAXYS Number:
4158948
EC Number:
200-517-3
MDL number:
MFCD00012605
UNSPSC Code:
12352200
PubChem Substance ID:
329770026

agency

USP/NF
tested according to Ph. Eur.

form

powder

mp

143-145 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBR9623V
BCBP3321V
BCBM7352V
BCBK5704V
BCBG5677V

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Dale A Currigan et al.
Anesthesiology, 121(5), 930-936 (2014-09-10)
Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right
C A Boly et al.
British journal of anaesthesia, 111(5), 750-758 (2013-07-11)
Left-ventricular end-systolic elastance (Ees) is an index of cardiac contractility, but the invasive nature of its assessment has limited perioperative application. We explored the feasibility of a minimally invasive method of Ees estimation for perioperative assessment of cardiac function and
Stephanie W Watts et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(6), 1320-1328 (2013-04-06)
Obesity and hypertension are comorbid in epidemic proportion, yet their biological connection is largely a mystery. The peptide chemerin is a candidate for connecting fat deposits around the blood vessel (perivascular adipose tissue) to arterial contraction. We presently tested the
P F Soeding et al.
British journal of anaesthesia, 111(2), 229-234 (2013-03-23)
The upright sitting or beachchair position is associated with hypotension, risk of cerebral hypoperfusion, and cerebral injury. We hypothesized that by increasing arterial pressure with phenylephrine administration, cerebral perfusion, and postoperative recovery would be improved. Thirty-four patients undergoing elective shoulder
Ke Jiang et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(52), E5716-E5723 (2014-12-17)
Inherited photoreceptor degenerations (IPDs), a group of incurable progressive blinding diseases, are caused by mutations in more than 200 genes, but little is known about the molecular pathogenesis of photoreceptor (PR) death. Increased retinal expression of STAT3 has been observed
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Chromatograms

application for HPLC

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