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Supelco

Piperacillin sodium salt

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C23H26N5NaO7S
CAS Number:
59703-84-3
Molecular Weight:
539.54
Beilstein/REAXYS Number:
5373920
EC Number:
261-868-6
MDL number:
MFCD00917471
UNSPSC Code:
41116107
PubChem Substance ID:
329770207
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥94% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C([O-])=O)c4ccccc4)C(=O)C1=O

InChI

1S/C23H27N5O7S.Na/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28;/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34);/q;+1/p-1/t13-,14-,15+,20-;/m1./s1

InChI key

WCMIIGXFCMNQDS-IDYPWDAWSA-M

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General description

Piperacillin sodium is a semi-synthetic penicillin which belongs to the β-lactam class of antibiotics with a broad spectrum of antibacterial activity against anaerobic pathogens and both gram positive and gram negative bacteria.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH8646
BCCF8960
BCCC4002
BCCC4003
BCBX6057

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Piperacillin therapy for serious bacterial infections.
Winston DJ, et al.
The American Journal of Medicine, 69(2), 255-261 (1980)
Piperacillin sodium: antibacterial spectrum, pharmacokinetics, clinical efficacy, and adverse reactions.
Fortner CL, et al.
Pharmacotherapy, 2(6), 287-298 (1982)
T W Felton et al.
Clinical pharmacology and therapeutics, 96(4), 438-448 (2014-06-14)
Pulmonary infections in critically ill patients are common and are associated with high morbidity and mortality. Piperacillin-tazobactam is a frequently used therapy in critically ill patients with pulmonary infection. Antibiotic concentrations in the lung reflect target-site antibiotic concentrations in patients
Erlangga Yusuf et al.
Journal of critical care, 29(6), 1089-1095 (2014-09-03)
The purpose of this study is to review the rationale of prolonged (ie, extended or continuous) infusion of piperacillin/tazobactam (PIP/TAZ) in critically ill patients and to perform a systematic review that compare the effectiveness of prolonged infusion with intermittent bolus
Chandra Datta Sumi et al.
The Journal of antimicrobial chemotherapy, 75(9), 2633-2640 (2020-06-26)
To compare bacterial killing and the emergence of resistance to piperacillin/tazobactam, administered by intermittent versus prolonged infusion (i.e. extended or continuous), for ceftriaxone-resistant Klebsiella pneumoniae clinical isolates in an in vitro dynamic hollow-fibre infection model (HFIM). K. pneumoniae 68 (Kp68;
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