A3139
Albumin from mouse serum
lyophilized powder, ≥96% (agarose gel electrophoresis)
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Synonym(s):
Mouse albumin
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biological source
mouse
Quality Level
assay
≥96% (agarose gel electrophoresis)
form
lyophilized powder
technique(s)
ELISA: suitable
electrophoresis: suitable
UniProt accession no.
storage temp.
2-8°C
Gene Information
mouse ... ALB(11657)
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General description
Mouse albumin gene is mapped to mouse chromosome 5. It codes for an albumin, which is the most prominent protein in the blood plasma. Albumin is produced by the mature liver. Mouse albumin gene promoter region includes minimum six binding sites (A to F) for specific DNA-binding proteins.
Application
Albumin from mouse serum has been used in labelling by probe 2 for the characterization of matrix metalloprotease-12 by one-dimensional electrophoresis. It has also been used for the preparation of calibrator and controls in enzyme-linked immunosorbent assay (ELISA).
Biochem/physiol Actions
Albumin facilitates the formation of cytoplasmic lipid droplets in pancreatic stellate cells and adipocyte differentiation of 3T3-L1 cells. In addition, it effectively regulates biological activity of adipogenic transcription factors, peroxisome proliferator-activated receptor (PPAR - γ ) and (CCAAT/enhancer binding protein (C/EBP).
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Detection of endogenous matrix metalloprotease-12 active form with a novel broad spectrum activity-based probe
Nury C, et al.
The Journal of biological chemistry, 288(8), 5636-5644 (2013)
Softened food reduces weight loss in the streptozotocin-induced male mouse model of diabetic nephropathy
Norgaard SA, et al.
Laboratory Animals, 52(4), 373-383 (2018)
Albumin-binding domain from Streptococcus zooepidemicus protein Zag as a novel strategy to improve the half-life of therapeutic proteins
Cantante C, et al.
Journal of Biotechnology, 253(6), 23-33 (2017)
The interplay of DNA-binding proteins on the promoter of the mouse albumin gene
Lichtsteiner S, et al.
Cell, 51(6), 963-973 (1987)
Marina Pekmezovic et al.
PLoS pathogens, 17(10), e1010037-e1010037 (2021-10-29)
The opportunistic pathogen Candida glabrata is the second most frequent causative agent of vulvovaginal candidiasis (VVC), a disease that affects 70-75% of women at least once during their life. However, C. glabrata is almost avirulent in mice and normally incapable
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