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B2635

Supelco

Busulfan

analytical standard, for drug analysis

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Synonym(s):
1,4-Butanediol dimethanesulfonate
Linear Formula:
CH3SO2O(CH2)4OSO2CH3
CAS Number:
Molecular Weight:
246.30
Beilstein/REAXYS Number:
1791786
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard, for drug analysis

Quality Level

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

114-117 °C (lit.)

application(s)

forensics and toxicology
veterinary

format

neat

SMILES string

CS(=O)(=O)OCCCCOS(C)(=O)=O

InChI

1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

InChI key

COVZYZSDYWQREU-UHFFFAOYSA-N

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This Item
B1385B3022B1170000
vibrant-m

B2635

Busulfan

vibrant-m

B1385

Butoxamine hydrochloride

vibrant-m

B3022

Beclomethasone dipropionate

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B1170000

Busulfan

grade

analytical standard, for drug analysis

grade

analytical standard, for drug analysis

grade

analytical standard, for drug analysis

grade

pharmaceutical primary standard

application(s)

forensics and toxicology
veterinary

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

forensics and toxicology
veterinary

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

mp

114-117 °C (lit.)

mp

-

mp

-

mp

114-117 °C (lit.)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

-

General description

Busulfan is a bifunctional alkylating agent, which may find application in the treatment of chronic granulocytic leukemia.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1A - Muta. 1B - Repr. 1B

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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25G
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1000309185

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Arnon Nagler et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(28), 3549-3556 (2013-08-28)
Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) in adults with acute myelogenous leukemia (AML). Intravenous (IV) Bu has more predictable bioavailability and a
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We conducted a prospective cohort study testing the noninferiority of survival of ablative intravenous busulfan (IV-BU) vs ablative total body irradiation (TBI)-based regimens in myeloid malignancies. A total of 1483 patients undergoing transplantation for myeloid malignancies (IV-BU, N = 1025;

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