MilliporeSigma
All Photos(2)

Documents

M6752

Sigma-Aldrich

Methyl salicylate

ReagentPlus®, ≥99% (GC)

Sign Into View Organizational & Contract Pricing

Synonym(s):
2-Hydroxybenzoic acid methyl ester, Methyl 2-hydroxybenzoate, Oil of wintergreen, Wintergreen oil
Linear Formula:
2-(HO)C6H4CO2CH3
CAS Number:
Molecular Weight:
152.15
Beilstein:
971516
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

vapor density

5.26 (vs air)

Quality Level

vapor pressure

1 mmHg ( 54 °C)

product line

ReagentPlus®

Assay

≥99% (GC)

form

liquid

autoignition temp.

847 °F

refractive index

n20/D 1.536 (lit.)

bp

222 °C (lit.)

mp

−8-−7 °C (lit.)

density

1.174 g/mL at 25 °C (lit.)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

COC(=O)c1ccccc1O

InChI

1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3

InChI key

OSWPMRLSEDHDFF-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
W2745188433276631
Methyl salicylate ReagentPlus®, ≥99% (GC)

Sigma-Aldrich

M6752

Methyl salicylate

Methyl salicylate ≥98%, FCC, FG

Sigma-Aldrich

W274518

Methyl salicylate

Methyl salicylate tested according to Ph. Eur.

Sigma-Aldrich

84332

Methyl salicylate

Methyl salicylate analytical standard

Supelco

76631

Methyl salicylate

assay

≥99% (GC)

assay

≥98%

assay

-

assay

≥99.0% (GC)

form

liquid

form

liquid

form

liquid

form

-

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

flavors and fragrances

application(s)

-

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

Quality Level

200

Quality Level

400

Quality Level

100

Quality Level

100

vapor density

5.26 (vs air)

vapor density

5.26 (vs air)

vapor density

5.26 (vs air)

vapor density

5.26 (vs air)

General description

Methyl salicylate (MeSA) is a natural herbivore-induced plant volatile It is a naturally occurring product in trees, legumes, exotic plants, vegetables, berries, and the primary constituent of the oil of wintergreen. MeSA is produced from salicylic acid.

Application

Methyl salicylate has been used:
  • as a component of clarifying solution for treating Mongolian gerbil cochlea intact for immunofluorescence analysis
  • as a plant elicitor to test its effect on reducing the whitefly population from tomato plants
  • in the hyalinization of tissues for pulmonary angiography
  • in clearing tissues

Biochem/physiol Actions

Methyl salicylate plays an important role in fruit ripening. It is known to attract natural enemies of herbivores. MeSA inhibits the activity of aminocyclopropane-1-carboxylic acid synthase (ACC synthase) and aminocyclopropane-1-carboxylic acid oxidase (ACC oxidase) in plums and tomatoes, it can inhibit fungal infections and reduce chilling injury symptoms in fruits like pomegranates. This oil of wintergreen is of great interest in the tobacco industry as a flavorant. It has counter irritant and anti-inflammatory effects.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

204.8 °F - closed cup

Flash Point(C)

96 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 3

1 of 3

Methyl salicylate European Pharmacopoeia (EP) Reference Standard

Y0002083

Methyl salicylate

Sodium hydroxide BioXtra, ≥98% (acidimetric), pellets (anhydrous)

Sigma-Aldrich

S8045

Sodium hydroxide

Methyl anthranilate ≥98%, FCC, FG

Sigma-Aldrich

W268208

Methyl anthranilate

A novel mouse model of high flow-induced pulmonary hypertension-surgically induced by right pulmonary artery ligation
Zhang A, et al.
The Journal of Surgical Research, 208, 132-139 (2017)
Aspirin and the Salicylates (2013)
Active Ingredients Used in Cosmetics: Safety Survey (2008)
M Risoud et al.
European annals of otorhinolaryngology, head and neck diseases, 137(2), 145-150 (2020-02-23)
Immunofluorescence on cleared intact cochlea allows detailed analysis of the cochlear ultrastructure, while avoiding the problems of dissection and serial sections. Protocols have been developed for mice and Mongolian gerbils. This technical note proposes a detailed and optimised immunofluorescence protocol
Therapeutic Medications in Athletic Training (2007)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service