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M8429

Sigma-Aldrich

D-Mannitol

meets EP, FCC, USP testing specifications

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Synonym(s):
Mannite
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein/REAXYS Number:
1721898
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.71

agency

meets EP testing specifications
meets USP testing specifications

Quality Level

reg. compliance

meets FCC testing specifications

assay

≥96.0%

form

powder

quality

meets EP, FCC, USP testing specifications

impurities

<1 ppm Lead

color

white

useful pH range

5.0-6.5 (25 °C, 182 g/L)

mp

167-170 °C (lit.)

solubility

water: soluble 182 g/L at 20 °C (68 °F)

cation traces

Ni: <1 ppm

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-KVTDHHQDSA-N

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1 of 4

This Item
M964763559M1902
vibrant-m

M8429

D-Mannitol

-
vibrant-m

M9647

D-Mannitol

Essential Grade
vibrant-m

63559

D-Mannitol

Premium Grade
vibrant-m

M1902

D-Mannitol

-
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥96.0%

assay

-

assay

≥99.0% (sum of enantiomers, HPLC)

assay

≥98% (GC)

useful pH range

5.0-6.5 (25 °C, 182 g/L)

useful pH range

5.0-6.5 (25 °C, 182 g/L)

useful pH range

-

useful pH range

5.0-6.5 (25 °C, 182 g/L)

impurities

<1 ppm Lead

impurities

Reducing sugars, passes test, ≤0.0008 meq/g Titratable acid, ≤0.01% Insoluble matter

impurities

insoluble matter, passes filter test, reducing sugars, complies, ≤0.0072% free acid (as CH3COOH)

impurities

-

form

powder

form

powder

form

powder

form

powder

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)


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Heikki O Koskela et al.
Chest, 124(4), 1341-1349 (2003-10-14)
To compare the sensitivity and validity of mannitol, histamine, and cold air challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma. A prospective study. Seventeen patients with recently diagnosed, steroid-naive asthma who fulfilled the diagnostic criteria of Finnish
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Maria Badal Tejedor et al.
International journal of pharmaceutics, 486(1-2), 315-323 (2015-04-07)
Tablets are the most convenient form for drug administration. However, despite the ease of manufacturing problems such as powder adhesion occur during the production process. This study presents surface and structural characterization of tablets formulated with commonly used excipients (microcrystalline
Heikki O Koskela et al.
Chest, 124(6), 2171-2177 (2003-12-11)
To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma. A prospective study. Thirty-seven consecutive patients with recently diagnosed, steroid-naive, mild, or atypical asthma
Cecilio F Caldeira et al.
Nature communications, 5, 5365-5365 (2014-11-06)
Circadian rhythms enable plants to anticipate daily environmental variations, resulting in growth oscillations under continuous light. Because plants daily transpire up to 200% of their water content, their water status oscillates from favourable during the night to unfavourable during the

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