Skip to Content
MilliporeSigma
All Photos(1)

Documents

N9007

Supelco

Noscapine hydrochloride hydrate

analytical standard

Synonym(s):

Narcotine hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C22H23NO7 · HCl · xH2O
CAS Number:
912-60-7
Molecular Weight:
449.88 (anhydrous basis)
EC Number:
213-014-9
MDL number:
MFCD00149223
UNSPSC Code:
41116107
PubChem Substance ID:
329818691
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

221-223 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

O.Cl.COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34

InChI

1S/C22H23NO7.ClH.H2O/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H;1H2/t17-,18+;;/m1../s1

InChI key

ZYGSNVAGWKWKKI-WCRQIBMVSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Noscapine hydrochloride hydrate may be used as a reference standard in the determination of noscapine hydrochloride in the synthetic binary mixtures like chlorpheniramine-noscapine and chlorpheniramine-guaiphenesin using derivative spectrophotometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000309816
0000234662
0000191750
SLCH3288
SLCB6101

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry.
Pappano B N, et al.
Talanta, 44(4), 633-639 (1997)
Patricia López et al.
Food chemistry, 242, 443-450 (2017-10-19)
A straightforward method to determine the content of six opium alkaloids (morphine, codeine, thebaine, noscapine, papaverine and narceine) in poppy seeds and bakery products was developed and validated down to a limit of quantification (LOQ) of 0.1mg/kg. The method was
Ana Amaral et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Endometrosis is a reproductive pathology that is responsible for mare infertility. Our recent studies have focused on the involvement of neutrophil extracellular traps enzymes, such as elastase (ELA), in the development of equine endometrosis. Noscapine (NOSC) is an alkaloid derived
Ana Amaral et al.
Life (Basel, Switzerland), 11(10) (2021-10-24)
Cathepsin G (CAT) is a protease released by neutrophils when forming neutrophil extracellular traps that was already associated with inducing type I collagen (COL1) in equine endometrium in vitro. Endometrosis is a fibrotic condition mainly characterized by COL1 deposition in
Srinivasa M Sammeta et al.
Pharmaceutical development and technology, 20(2), 169-175 (2013-11-14)
The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches. Different combinations of co-solvents, which were selected on the basis of high-throughput solubility screening, were

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service