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NIST3950

Vitamin B6 in frozen human serum

NIST® SRM® 3950

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NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

packaging

pkg of 2 vials, 1 level ea

manufacturer/tradename

NIST®

technique(s)

mass spectrometry (MS): suitable

application(s)

clinical testing

format

matrix material

storage temp.

−70°C

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NIST3950

Vitamin B6 in frozen human serum

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Human Serum

grade

certified reference material

grade

certified reference material

grade

certified reference material

grade

certified reference material

application(s)

clinical testing

application(s)

clinical testing

application(s)

clinical testing

application(s)

clinical testing

format

matrix material

format

matrix material

format

matrix material

format

matrix material

form

liquid

form

liquid

form

liquid

form

liquid

packaging

pkg of 2 vials, 1 level ea

packaging

pkg of set(4) (2 ea conc)

packaging

pkg of 6 x 2.0 mL

packaging

pkg of 3 x 2 mL

General description

Pyridoxal 5′-phosphate (PLP) is the major circulating form of vitamin B6 and the most common direct measure of this vitamin in serum or plasma. A unit of the vitamin B6 standard reference material (SRM) 3950 consists of two stoppered vials of frozen human serum, one vial each at two different concentration levels. Each vial contains 1.0 mL of human serum.

SRM 3950_cert

SRM 3950 _SDS

Application

Vitamin B6 in frozen human serum standard reference material (SRM) 3950 is intended primarily for use in evaluating the accuracy of procedures for the determination of the vitamin B6 metabolite pyridoxal 5′-phosphate (PLP) in human serum. It is also intended for use in validating working or secondary reference materials.

Features and Benefits

The use of this material will provide confidence in the assignment of values to the in-house assay calibrators.

Preparation Note

  • SRM 3950 is provided as a frozen serum that should be allowed to thaw at room temperature (20 °C to 25 °C) under subdued light.
  • After the material is thawed, it should be used immediately.
  • The contents of the vial should then be gently mixed prior to the removal of a test portion for analysis.
  • Precautions should be taken to expose serum only under subdued lighting conditions.

Other Notes

  • SRM 3950 is intended for research use.
  • Details on expiration, storage, safety, usage, and source are provided in the NIST certificate
  • Information on biomaterials, disposal, and transport is available in the SDS

Legal Information

NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Xiaochun Zhang et al.
Practical laboratory medicine, 21, e00160-e00160 (2020-04-30)
Vitamin B6 deficiency is associated with a wide spectrum of clinical syndromes. While vitamin B6 status is primarily assessed by measuring the biologically active form of the vitamin, pyridoxal 5-phosphate (PLP), concurrent measurement of the final metabolite 4-pyridoxic acid (PA)

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