NIST3950
Vitamin B6 in frozen human serum
NIST® SRM® 3950
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About This Item
Recommended Products
grade
certified reference material
Quality Level
form
liquid
packaging
pkg of 2 vials, 1 level ea
manufacturer/tradename
NIST®
technique(s)
mass spectrometry (MS): suitable
application(s)
clinical testing
format
matrix material
storage temp.
−70°C
General description
Pyridoxal 5′-phosphate (PLP) is the major circulating form of vitamin B6 and the most common direct measure of this vitamin in serum or plasma. A unit of the vitamin B6 standard reference material (SRM) 3950 consists of two stoppered vials of frozen human serum, one vial each at two different concentration levels. Each vial contains 1.0 mL of human serum.
SRM 3950_cert
SRM 3950 _SDS
SRM 3950_cert
SRM 3950 _SDS
Application
Vitamin B6 in frozen human serum standard reference material (SRM) 3950 is intended primarily for use in evaluating the accuracy of procedures for the determination of the vitamin B6 metabolite pyridoxal 5′-phosphate (PLP) in human serum. It is also intended for use in validating working or secondary reference materials.
Features and Benefits
The use of this material will provide confidence in the assignment of values to the in-house assay calibrators.
Preparation Note
- SRM 3950 is provided as a frozen serum that should be allowed to thaw at room temperature (20 °C to 25 °C) under subdued light.
- After the material is thawed, it should be used immediately.
- The contents of the vial should then be gently mixed prior to the removal of a test portion for analysis.
- Precautions should be taken to expose serum only under subdued lighting conditions.
Other Notes
- SRM 3950 is intended for research use.
- Details on expiration, storage, safety, usage, and source are provided in the NIST certificate
- Information on biomaterials, disposal, and transport is available in the SDS
Legal Information
NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Practical laboratory medicine, 21, e00160-e00160 (2020-04-30)
Vitamin B6 deficiency is associated with a wide spectrum of clinical syndromes. While vitamin B6 status is primarily assessed by measuring the biologically active form of the vitamin, pyridoxal 5-phosphate (PLP), concurrent measurement of the final metabolite 4-pyridoxic acid (PA)
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