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P2126

Sigma-Aldrich

L-Phenylalanine

reagent grade, ≥98%

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Synonym(s):
(S)-2-Amino-3-phenylpropionic acid
Linear Formula:
C6H5CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
165.19
Beilstein/REAXYS Number:
1910408
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

grade

reagent grade

Quality Level

assay

≥98%

form

powder or crystals

color

white to off-white

mp

270-275 °C (dec.) (lit.)

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

application(s)

detection

SMILES string

N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

InChI key

COLNVLDHVKWLRT-QMMMGPOBSA-N

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1 of 4

This Item
P5482W358509W358512
vibrant-m

P2126

L-Phenylalanine

Essential Grade
vibrant-m

P5482

L-Phenylalanine

Premium Grade
vibrant-m

W358509

L-Phenylalanine

-
vibrant-m

W358512

L-Phenylalanine

-
form

powder or crystals

form

powder

form

-

form

-

assay

≥98%

assay

98.5-101.0%

assay

99%

assay

99%

Quality Level

200

Quality Level

300

Quality Level

400

Quality Level

400

color

white to off-white

color

white

color

-

color

-

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

solubility

1 M HCl: 50 mg/mL

solubility

H2O: soluble 16.5 g/L at 20 °C (completely)

solubility

-

Application

L-Phenylalanine has been used in Fluo-4 Ca2+-assay in a study to demonstrate that G-protein coupled receptor 139 reference surrogate agonists 1a and 7c and L-phenylalanine share a common binding site. It has also been used to spike blood samples to study the effect of dried blood spots on newborn screening.

Biochem/physiol Actions

L-Phenylalanine is an essential aromatic amino acid. It has a role in metabolism as it forms a starting point for many pathways. This neutral amino acid is a precursor for tyrosine, epinephrine, dopamine and norepinephrine.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Anne Cathrine
Scientific Reports (2017)
Effect of Dried Blood Spot Quality on Newborn Screening Analyte Concentrations and Recommendations for Minimum Acceptance Criteria for Sample Analysis
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