PHR1615

Ritodrine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Ritodrine hydrochloride, 1-(4-Hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethylamino]propanol, N-(p-Hydroxyphenethyl)-4-hydroxynorephedrine hydrochloride
• Empirical Formula (Hill Notation): C₁₇H₂₁NO₃ · HCl
• CAS Number: 23239-51-2
• Molecular Weight: 323.81
• EC Number: 245-514-8
• MDL number: MFCD01657514
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823511
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to Ph. Eur. 586; traceable to USP 1604701
• API family: ritodrine
• CofA: current certificate can be downloaded
• packaging: pkg of 1 g
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.C[C@H](NCCc1ccc(O)cc1)[C@H](O)c2ccc(O)cc2
• InChI: 1S/C17H21NO3.ClH/c1-12(17(21)14-4-8-16(20)9-5-14)18-11-10-13-2-6-15(19)7-3-13;/h2-9,12,17-21H,10-11H2,1H3;1H/t12-,17-;/m0./s1
• InChI key: IDLSITKDRVDKRV-XHXSRVRCSA-N

Description

General description

Ritodrine Hydrochloride is a potent tocolytic drug and a selective γ₂-adrenoceptor agonist, widely used for the control of premature labor.

Application

Ritodrine Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3901 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable