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Key Documents

T0010000

Talampicillin hydrochloride

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C24H23N3O6S · HCl
CAS Number:
39878-70-1
Molecular Weight:
517.98
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

talampicillin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

S1[C@H]2N([C@H](C1(C)C)C(=O)OC4OC(=O)c5c4cccc5)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.[Cl-].[H+]

InChI

1S/C24H23N3O6S.ClH/c1-24(2)17(22(31)33-23-14-11-7-6-10-13(14)21(30)32-23)27-19(29)16(20(27)34-24)26-18(28)15(25)12-8-4-3-5-9-12;/h3-11,15-17,20,23H,25H2,1-2H3,(H,26,28);1H/t15-,16-,17+,20-,23?;/m1./s1

InChI key

PAZSYTCTHYSIAO-WVFSJLEKSA-N

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Talampicillin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Kinetics of thermal decomposition of talampicillin hydrochloride in the solid state.
E Pawełczyk et al.
Die Pharmazie, 55(5), 390-391 (2002-02-07)
Ewaryst Pawełczyk et al.
Acta poloniae pharmaceutica, 59(1), 25-29 (2002-05-25)
Talampicillin stability in aqueous solutions was studied in a broad range of pH values using as medium solutions of hydrochloric acid (pH 0.4-1.8), phosphate buffers (pH 2.05-3.13 and 6.03-8.04), acetate buffer (pH 3.87-5.28) and borate buffer (pH 8.90-9.10) as well
N Yamane et al.
The Tokai journal of experimental and clinical medicine, 11(2), 91-99 (1986-05-01)
Parameters for blood concentrations of the peroral antibiotics talampicil in and bacampicillin, in NZW rabbits were determined using a two compartment model. On the basis of these pharmacokinetic parameters, a three compartment model was prepared for the concentrations of these
J Sjövall et al.
Antimicrobial agents and chemotherapy, 20(6), 837-838 (1981-12-01)
A 200-mg amount of bacampicillin showed a significantly higher relative extent of bioavailability than did a 250-mg amount of talampicillin, possibly due to their different stability in the digestive juices.
[In vitro hydrolysis of an ampicillin ester. I. Microbiologic evaluation].
N M Angelini et al.
Revista latinoamericana de microbiologia, 25(2), 109-112 (1983-04-01)
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