Name: Gemifloxacin mesylate
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₀FN₅O₄ · CH₄O₃S

CAS Number:

210353-53-0

Molecular Weight:

485.49

MDL number:

MFCD08277637

UNSPSC Code:

12352200

PubChem Substance ID:

329825509

NACRES:

NA.77

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Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

H₂O: 10 mg/mL, clear

storage temp.

room temp

SMILES string

CS(=O)(O)=O.OC(C1=CN(C2CC2)C3=NC(N4C/C(C(CN)C4)=N\OC)=C(F)C=C3C1=O)=O

InChI

1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+;

InChI key

JIYMVSQRGZEYAX-CWUUNJJBSA-N

Biochem/physiol Actions

Gemifloxacin is a broad-spectrum quinolone antibacterial.

Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.

pictograms

GHS08

signalword

Warning

hcodes

H341,H361d,H373

pcodes

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Muta. 2 - Repr. 2 - STOT RE 2

target_organs

Liver

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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