Y0001779

Histamine

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 2-(4-Imidazolyl)ethylamine
• Empirical Formula (Hill Notation): C₅H₉N₃
• CAS Number: 51-45-6
• Molecular Weight: 111.15
• Beilstein/REAXYS Number: 2012
• MDL number: MFCD00005210
• UNSPSC Code: 12352116
• PubChem Substance ID: 329831568
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: histamine
• manufacturer/tradename: EDQM
• bp: 167 °C/0.8 mmHg (lit.)
• mp: 83-84 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: NCCc1c[nH]cn1
• InChI: 1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
• InChI key: NTYJJOPFIAHURM-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Histamine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Endogenous H₁ and H₂ histamine receptor agonist; H₁ activation mobilizes Ca²⁺; H₂ activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H315,H317,H319,H334,H335
• pcodes: P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable