213330

Ammonium chloride

ACS reagent, ≥99.5%

• Synonym(s): Salmiac
• Linear Formula: NH₄Cl
• CAS Number: 12125-02-9
• Molecular Weight: 53.49
• Beilstein/REAXYS Number: 4371014
• EC Number: 235-186-4
• MDL number: MFCD00011420
• UNSPSC Code: 12352300
• eCl@ss: 38050207
• PubChem Substance ID: 329752144
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• agency: suitable for SM 5210
• vapor density: 1.9 (vs air)
• vapor pressure: 1 mmHg ( 160.4 °C)
• assay: ≥99.5%
• form: powder, crystals or chunks
• impurities: ≤0.005% insolubles
• ign. residue: ≤0.01%
• pH: 4.5-5.5 (25 °C, 5%)
• mp: 340 °C (subl.) (lit.)
• anion traces: phosphate (PO₄^3-): ≤2 ppm; sulfate (SO₄^2-): ≤0.002%
• cation traces: Ca: ≤0.001%; Fe: ≤2 ppm; Mg: ≤5 ppm; heavy metals: ≤5 ppm (by ICP)
• SMILES string: N.Cl
• InChI: 1S/ClH.H3N/h1H;1H3
• InChI key: NLXLAEXVIDQMFP-UHFFFAOYSA-N

Description

General description

Crystals of ammonium chloride (NH₄Cl) belong to the cubic crystal system. It can be synthesized by reacting HCl with aqueous ammonia solutions. NH₄Cl is formed as a by-product during soda manufactured by Solvay process.

Application

Ammonium chloride (NH₄Cl) has been used as one of the components of red blood cell (RBC) lysis buffer for use in various studies. It may be used as a catalyst in the preparation 3,4-dihydropyrimidin-2-(1H)-ones.
Inorganic ammonium ions (NH₄⁺) effectively catalyze the aldol condensation of carbonyl compounds. It serves as a source of nitrogen during the preparation of trimethylamine hydrochloride (TMA·HCl).

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 - H319
• pcodes: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable