30326
EMPIGEN® BB detergent
~30% active substance
Synonym(s):
N,N-Dimethyl-N-dodecylglycine betaine, N-(Alkyl C10-C16)-N,N-dimethylglycine betaine
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About This Item
Linear Formula:
CH3(CH2)8-14CH2N+(CH3)2CH2COO-
CAS Number:
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
266-368-1
Beilstein/REAXYS Number:
3670807
MDL number:
description
zwitterionic
Quality Level
form
liquid
composition
solid content, 35.0-45.0 % (w/v)
concentration
~30% active substance
CMC
1.6-2.1 mM (20-25°C)
density
1.030-1.060 g/mL at 20 °C
UV absorption
λ: 417 nm Amax: ≤0.055, λ: 441 nm Amax: ≤0.037
SMILES string
CCCCCCCCCCCC[N+](C)(C)CC([O-])=O
InChI
1S/C16H33NO2/c1-4-5-6-7-8-9-10-11-12-13-14-17(2,3)15-16(18)19/h4-15H2,1-3H3
InChI key
DVEKCXOJTLDBFE-UHFFFAOYSA-N
Application
Empigen BB is a zwitterionic detergent compatible with anionic, non-ionic, cationic and other amphoteric surfactants.
Empigen BB is a useful detergent that has been used in the solubilization of membrane proteins and biochemical analysis of keratins. It not only helps to solubilize bigger amounts of protein but it also maintains antibody reactivity. It has been also used in the purification of leucine-rich repeat kinase 2 (LRRK2) in Escherichia coli during research in Parkinson′s disease. The use of Empigen in the preparation of viral antigens is being increasing due to its effectivity in giving greater antibody responses.
Empigen BB is a useful detergent that has been used in the solubilization of membrane proteins and biochemical analysis of keratins. It not only helps to solubilize bigger amounts of protein but it also maintains antibody reactivity. It has been also used in the purification of leucine-rich repeat kinase 2 (LRRK2) in Escherichia coli during research in Parkinson′s disease. The use of Empigen in the preparation of viral antigens is being increasing due to its effectivity in giving greater antibody responses.
Legal Information
EMPIGEN is a registered trademark of Huntsman Corporation
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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R Jennings et al.
Journal of medical virology, 31(2), 98-108 (1990-06-01)
HSV-1 antigen preparations solubilised from Vero cells by using either the non-ionic detergent Nonidet P40 or the zwitterionic detergent Empigen BB, and purified on sucrose density gradients or over a sucrose cushion, were tested by ELISA with anti-HSV-1 glycoprotein monoclonal
Adam M Rotunda et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 30(7), 1001-1008 (2004-06-24)
Phosphatidylcholine injections are becoming an increasingly popular technique to treat localized fat accumulation. This formula is composed primarily of phosphatidylcholine and sodium deoxycholate, a bile salt used to solubilize the natural phospholipid in water. The mechanism through which this injectable
L A Lowthert et al.
Biochemical and biophysical research communications, 206(1), 370-379 (1995-01-05)
Intermediate filament (IF) proteins make up some of the most insoluble proteins known, and within the IF protein family, keratins are the least soluble. We compared the efficiency of nonionic, cationic, mixed nonionic and anionic, and zwitterionic detergents in solubilizing
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 30326-50ML | 04061826666333 |
| 30326-250ML | 04061826666326 |