Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

75447

Sigma-Aldrich

2-Oxoadipic acid

≥95.0% (HPLC)

Synonym(s):

α-Ketoadipic acid, 2-Oxoadipate, 2-Oxohexanedioic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H8O5
CAS Number:
3184-35-8
Molecular Weight:
160.12
MDL number:
MFCD00010004
UNSPSC Code:
12352106
PubChem Substance ID:
329766428
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

100

assay

≥95.0% (HPLC)
≥97.0% (T)

form

powder

lipid type

saturated FAs

Storage temp.

2-8°C

SMILES string

OC(=O)CCCC(=O)C(O)=O

InChI

1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)

Inchi Key

FGSBNBBHOZHUBO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
G9880G2751K1502
Glutamic-Pyruvic Transaminase from porcine heart lyophilized powder, ≥75 units/mg protein

G8255

Glutamic-Pyruvic Transaminase from porcine heart

Glutamic-Pyruvic Transaminase from porcine heart ammonium sulfate suspension, ≥75 units/mg protein

G9880

Glutamic-Pyruvic Transaminase from porcine heart

Glutamic-Oxalacetic Transaminase from porcine heart Type I, ammonium sulfate suspension, 200-500 units/mg protein

G2751

Glutamic-Oxalacetic Transaminase from porcine heart

α-Ketoglutarate Dehydrogenase from porcine heart buffered aqueous glycerol solution, 0.1-1.0 units/mg protein (Lowry)

K1502

α-Ketoglutarate Dehydrogenase from porcine heart

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

-

biological source

Porcine heart

biological source

Porcine heart

biological source

-

biological source

-

specific activity

≥75 units/mg protein

specific activity

≥75 units/mg protein

specific activity

200-500 units/mg protein

specific activity

0.1-1.0 units/mg protein (Lowry)

form

lyophilized powder

form

ammonium sulfate suspension

form

ammonium sulfate suspension

form

buffered aqueous glycerol solution

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

foreign activity

L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%, glutamic-oxalacetic transaminase ≤0.1%

foreign activity

L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%, glutamic-oxalacetic transaminase ≤0.05%

foreign activity

glutamic-pyruvic transaminase ≤0.03%, lactic dehydrogenase ≤0.01%, malic dehydrogenase ≤0.01%

foreign activity

pyruvate dehydrogenase ≤20%

Application


  • Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate: Showcases the application of 2-oxoadipic acid in enzyme engineering, enhancing biocatalytic processes for the production of novel compounds, vital for pharmaceutical and chemical industries (Tariq et al., 2022).

Biochem/physiol Actions

Important metabolite between the TCA cycle and lysine biosynthesis. Of interest for research on mitochondrial metabolite transporters.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM3755
BCCG9094
BCBQ8969V
BCBH4492V
1398444V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Pyroglutamic Acid United States Pharmacopeia (USP) Reference Standard

USP

1589029

Pyroglutamic Acid

Nikolaus Sonnenschein et al.
BMC systems biology, 6, 41-41 (2012-05-16)
Integrating gene expression profiles and metabolic pathways under different experimental conditions is essential for understanding the coherence of these two layers of cellular organization. The network character of metabolic systems can be instrumental in developing concepts of agreement between expression
D Darmaun et al.
Journal of chromatography, 620(1), 33-38 (1993-10-22)
A method is described for measuring glutamine (GLN) and alpha-ketoglutarate (KG) concentration and specific activity (SA) using high-performance liquid chromatography (HPLC). Plasma GLN and KG are separated on miniature ion-exchange columns. KG is derivatized with O-phenylene diamine, the derivative is
Andrea Schulze-Bergkamen et al.
Pediatric research, 58(5), 873-880 (2005-09-27)
Organic acid (OAD) and fatty acid oxidation disorders (FAOD) are inborn errors of metabolism often presenting with life-threatening metabolic decompensation followed by (irreversible) organ failure, and even death during catabolic state. Most of these diseases are considered as treatable, and
A fatal case of 2-keto-, 2-hydroxy- and 2-aminoadipic aciduria: relation of organic aciduria to phenotype?
C Jakobs et al.
Journal of inherited metabolic disease, 15(2), 279-280 (1992-01-01)
D G Hine et al.
Biomedical mass spectrometry, 11(7), 332-339 (1984-07-01)
Numerous abnormal metabolites were identified in large amounts in the urine of hypoglycin-treated rats using capillary gas chromatography/mass spectrometry-computer analysis. These metabolites are not detectable in significant amounts in normal rats' urine. Ten of them have not been previously associated
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service