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75890

Sigma-Aldrich

α-Ketoglutaric acid

99.0-101.0% (T)

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Synonym(s):
alpha-Ketoglutarate, alpha-Ketoglutaric acid, 2-Oxoglutaric acid, 2-Oxopentanedioic acid
Linear Formula:
HOOCCH2CH2COCOOH
CAS Number:
Molecular Weight:
146.10
Beilstein/REAXYS Number:
1705689
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99.0-101.0% (T)

form

crystals

mp

114-118 °C

solubility

H2O: 1 g/10 mL, clear to slightly hazy, colorless to almost colorless

storage temp.

2-8°C

SMILES string

OC(=O)CCC(=O)C(O)=O

InChI

1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

InChI key

KPGXRSRHYNQIFN-UHFFFAOYSA-N

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This Item
K1750K1128O4126
α-Ketoglutaric acid 99.0-101.0% (T)

75890

α-Ketoglutaric acid

α-Ketoglutaric acid ≥98.5% (NaOH, titration)

K1750

α-Ketoglutaric acid

α-Ketoglutaric acid BioReagent, suitable for cell culture, suitable for insect cell culture

K1128

α-Ketoglutaric acid

Oxaloacetic acid ≥97% (HPLC)

O4126

Oxaloacetic acid

Quality Level

300

Quality Level

200

Quality Level

-

Quality Level

200

solubility

H2O: 1 g/10 mL, clear to slightly hazy, colorless to almost colorless

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to almost colorless

solubility

H2O: 100 mg/mL, clear to slightly hazy, colorless to light yellow

mp

114-118 °C

mp

-

mp

-

mp

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

form

crystals

form

powder

form

powder or crystals

form

powder

General description

α-Ketoglutaric acid is a 2-oxocarboxylic acid (2-OCA) that is formed as a metabolite in the Kreb′s cycle.

Application

α-ketoglutaric acid along with L-arginine can undergo reduction with sodium cyanoborohydride to form the diastereomers, nopaline and isonopaline.

Other Notes

Reagent for the analysis of tryptophan; Substrate for glutamate dehydrogenase

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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