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MilliporeSigma

A7430

Azadirachtin

~95%

Synonym(s):

azadirachtin A

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About This Item

Empirical Formula (Hill Notation):
C35H44O16
CAS Number:
Molecular Weight:
720.71
MDL number:
UNSPSC Code:
12352212
PubChem Substance ID:
NACRES:
NA.28
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assay

~95%

Quality Level

form

solid

application(s)

agriculture
environmental

storage temp.

−20°C

SMILES string

[H]C1([H])C2OC3([H])OC=CC3(O)C1C4(C)OC24[C@@]5(C)[C@@H](O)[C@@H]6OC[C@]7([C@H](C[C@H](OC(=O)C(C)=CC)[C@]8(COC(O)([C@H]58)C(=O)OC)[C@@]67[H])OC(C)=O)C(=O)OC

InChI

1S/C35H44O16/c1-8-15(2)24(38)49-18-12-19(48-16(3)36)32(26(39)43-6)13-46-21-22(32)31(18)14-47-34(42,27(40)44-7)25(31)29(4,23(21)37)35-20-11-17(30(35,5)51-35)33(41)9-10-45-28(33)50-20/h8-10,17-23,25,28,37,41-42H,11-14H2,1-7H3/t17?,18-,19?,20?,21+,22+,23?,25?,28?,29?,30?,31?,32-,33?,34-,35?/m0/s1

InChI key

FTNJWQUOZFUQQJ-CFYAVYSVSA-N

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Application

Azadirachtin has been used as a standard for high performance liquid chromatography (HPLC) and for quantification in suspension cultures of Azadirachta indica (A. Juss).

Biochem/physiol Actions

Triterpenoid found in need tree seeds, azadiractin suppresses feeding by many insect species and disrupts growth of most insect and other arthropod species, while having very low mammalian toxicity. Promising as a natural pesticide.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Statistical media optimization for cell growth and azadirachtin production in Azadirachta indica (A. Juss) suspension cultures
Prakash G and Srivastava AK
Process Biochemistry (Oxford, United Kingdom), 40(12), 3795-3800 (2005)
Benshui Shu et al.
Scientific reports, 7(1), 13231-13231 (2017-10-19)
As an important botanical pesticide, azadirachtin demonstrates broad insecticidal activity against many agricultural pests. The results of a previous study indicated the toxicity and apoptosis induction of azadirachtin in Spodoptera frugiperda Sf9 cells. However, the lack of genomic data has
Torranis Ruttanaphan et al.
Insects, 11(10) (2020-10-15)
Spodoptera frugiperda, a highly polyphagous insect pest from America, has recently invaded and widely spread throughout Africa and Asia. Effective and environmentally safe tools are needed for successful pest management of this invasive species. Natural molecules extracted from plants offer
Cecilia Stahl Vieira et al.
Developmental and comparative immunology, 114, 103864-103864 (2020-09-13)
Rhodnius prolixus is an insect vector of two flagellate parasites, Trypanosoma rangeli and Trypanosoma cruzi, the latter being the causative agent of Chagas disease in Latin America. The R. prolixus neuroendocrine system regulates the synthesis of the steroid hormone ecdysone
Daniel Bernardi et al.
Pest management science, 69(1), 75-80 (2012-07-19)
The spider mite, Tetranychus urticae, is the major strawberry pest in Brazil. The main strategies for its control comprise synthetic acaricides and predatory mites. The recent register of a commercial formula of azadirachtin (Azamax(®) 12 g L(-1) ) can be

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