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A9125

Sigma-Aldrich

Nα-Acetyl-L-glutamine

≥98% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C7H12N2O4
CAS Number:
2490-97-3
Molecular Weight:
188.18
Beilstein/REAXYS Number:
1727471
EC Number:
219-647-7
MDL number:
MFCD00038159
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24891229
NACRES:
NA.26

product name

Nα-Acetyl-L-glutamine,

assay

≥98% (TLC)

form

powder

color

white

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C7H12N2O4/c1-4(10)9-5(7(12)13)2-3-6(8)11/h5H,2-3H2,1H3,(H2,8,11)(H,9,10)(H,12,13)/t5-/m0/s1

InChI key

KSMRODHGGIIXDV-YFKPBYRVSA-N

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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I Magnusson et al.
Metabolism: clinical and experimental, 38(8 Suppl 1), 82-88 (1989-08-01)
L-glutamine is too unstable for inclusion in solutions for parenteral nutrition, but its acetylated analogue, N-acetyl-L-glutamine is not. The purpose of this three-part study was to investigate the utilization of intravenously (IV) administered acetylglutamine in humans. In study 1, nine
Cecilia Roux et al.
Oncotarget, 8(56), 95361-95376 (2017-12-10)
Pancreatic ductal adenocarcinoma (PDAC) is becoming the second leading cause of cancer-related death in the Western world. The mortality is very high, which emphasizes the need to identify biomarkers for early detection. As glutamine metabolism alteration is a feature of
Alexandra Arnaud et al.
Clinical nutrition (Edinburgh, Scotland), 23(6), 1303-1312 (2004-11-24)
Glutamine instability in liquid media suggests that evaluation of reasonable enteral nutrition sources of glutamine is needed. N-acetyl-l-glutamine offers no instability and no intolerance problems. This research was conducted to study the absorption and apparent digestibility of glutamine versus N-acetyl-l-glutamine.
F Drago et al.
Clinical neuropharmacology, 13(4), 290-296 (1990-08-01)
The pyrimidine nucleosides uridine (URI) and cytidine (CYT), alone or associated with n-acetyl-glutamine (NAG), were injected acutely or subchronically to aged (26 months old) male rats of the Sprague-Dawley strain. Learning and memory abilities of the animals were studied with
José M López-Pedrosa et al.
Digestive diseases and sciences, 52(3), 650-658 (2007-01-27)
The goal of this study was to evaluate the preventive effect of free glutamine versus N-acetyl-L-glutamine, a liquid-stable source of glutamine, on gut damage induced by protein energy malnutrition in pigs. Healthy pigs (n = 6) were fed a liquid
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