B3303

Buserelin acetate salt

≥90% (HPLC)

• Synonym(s): des-Gly¹⁰-[D-Ser[t-Bu]⁶]-LH-RH ethylamide acetate salt, pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt acetate salt
• Empirical Formula (Hill Notation): C₆₀H₈₆N₁₆O₁₃ · C₂H₄O₂
• CAS Number: 68630-75-1
• Molecular Weight: 1299.48
• MDL number: MFCD00941414
• UNSPSC Code: 51111800
• NACRES: NA.32

Properties

• assay: ≥90% (HPLC)
• form: powder
• UniProt accession no.: P12391
• storage temp.: −20°C
• SMILES string: [nH]1cncc1C[C@H](NC(=O)[C@H]6NC(=O)CC6)C(=O)N[C@@H](Cc4c5c([nH]c4)cccc5)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc3ccc(cc3)O)C(=O)N[C@H](COC(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2[C@@H](CCC2)C(=O)NCC.OC(=O)C
• InChI: 1S/C60H86N16O13.C2H4O2/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40;1-2(3)4/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65);1H3,(H,3,4)/t40-,41-,42-,43-,44-,45-,46-,47+,48-;/m0./s1
• InChI key: PYMDEDHDQYLBRT-DRIHCAFSSA-N
• Gene Information: rat ... Chrnb3(171131)

Description

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ser-tBu-Leu-Arg-Pro-NHEt

Biochem/physiol Actions

Buserelin is an LH-RH agonist.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H360
• pcodes: P201 - P301 + P312 + P330 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges