Skip to Content
MilliporeSigma
All Photos(4)

Documents

B4679

Sigma-Aldrich

BIS-TRIS propane

BioPerformance Certified, suitable for cell culture, ≥99.0%

Synonym(s):

1,3-Bis[tris(hydroxymethyl)methylamino]propane

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH2[CH2NHC(CH2OH)3]2
CAS Number:
Molecular Weight:
282.33
Beilstein/REAXYS Number:
1786109
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

grade

BioPerformance Certified

Quality Level

assay

≥99.0%

form

crystals

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and bioburden, tested

useful pH range

6.3-9.5

pKa (25 °C)

(1) 6.8, (2) 9.0

mp

164-165 °C (lit.)

application(s)

diagnostic assay manufacturing

foreign activity

DNAse (exonuclease), NICKase (endonuclease), RNAse, and protease, none detected

SMILES string

OCC(CO)(CO)NCCCNC(CO)(CO)CO

InChI

1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2

InChI key

HHKZCCWKTZRCCL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

  • Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor.: BIS-TRIS propane is used in the development of nanowire field-effect transistors for detecting GC-rich RNA sequences. The study demonstrates the buffer′s role in enhancing the specificity and sensitivity of these biosensors (Chou et al., 2019).

  • Elimination of ghost peaks by optimization of anion exchange chromatography method for determination of gamma-carboxyglutamic acid (Gla)-domainless impurity in recombinant activated clotting factor VII drug products.: BIS-TRIS propane is employed in optimizing chromatography methods to eliminate ghost peaks during the analysis of pharmaceutical impurities. The buffer′s effectiveness ensures accurate and reliable detection of impurities in drug formulations (Tahmasbi et al., 2019).

Other Notes

Easily compare specifications for BIS-TRIS propane products with the BIS-TRIS propane specification table.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 8

1 of 8

MES sodium salt BioReagent, ≥99% (titration), crystalline

Sigma-Aldrich

M5057

MES sodium salt

ProClin™ 950 ProClin™ preservative for use in IVD manufacturing, pkg of 400 mL, MIT 9.5 %

Sigma-Aldrich

46879-U

ProClin 950

BIS-TRIS ≥98.0% (titration)

Sigma-Aldrich

B9754

BIS-TRIS

BIS-TRIS BioXtra, ≥98.0% (titration)

Sigma-Aldrich

B7535

BIS-TRIS

HEPES ≥99.5% (titration)

Sigma-Aldrich

H3375

HEPES

TERGITOL™ Type 15-S-9

Sigma-Aldrich

15S9

TERGITOL

MES low moisture content, ≥99% (titration)

Sigma-Aldrich

M3671

MES

R Tóth-Boconádi et al.
Biophysical journal, 78(6), 3170-3177 (2000-05-29)
Buffers change the electric signals of light-excited bacteriorhodopsin molecules in purple membrane if their concentration and the pH of the low-salt solution are properly selected. "Positive" buffers produce a positive component, and "negative" buffers a negative component in addition to
Michael C Breadmore
Journal of chromatography. A, 1217(24), 3900-3906 (2010-05-11)
An EOF counter-balanced ITP boundary has been used to stack anions from high conductivity samples during continuous electrokinetic injection of the sample. In a polystyrenesulfonate/poly(diallyldimethylammonium chloride) polyelectrolyte coated capillary, the time at which the ITP boundary exited the capillary could
E Csuhai et al.
Biochemistry, 34(38), 12411-12419 (1995-09-26)
A secreted dibasic cleaving peptidase capable of converting dynorphins into Leu-enkephalin-Arg6 was purified from the medium of EL-4 mouse thymoma cells. The enzyme is a novel metalloendopeptidase with a neutral pH optimum (6.9) and a molecular weight of approximately 130
R Coronado et al.
The Journal of general physiology, 79(4), 529-547 (1982-04-01)
A collection of organic cations has been used to probe the gross structural features of the ionic diffusion pathway in a K+-selective channel from sarcoplasmic reticulum (SR). Channels were incorporated into planar phospholipid bilayer membranes, and single-channel currents were measured
S J Smith et al.
The Journal of biological chemistry, 259(15), 9365-9368 (1984-08-10)
The kinetics of binding and hydrolysis of ATP by bovine cardiac myosin subfragment 1 has been reinvestigated. More than 90% of the total fluorescence amplitude associated with ATP hydrolysis occurs with an apparent second-order rate constant of 8.1 X 10(5)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service