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C3011

Sigma-Aldrich

Cesium chloride

Grade I, ≥99.0%

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Synonym(s):
Caesium monochloride, Cesium chloride
Linear Formula:
CsCl
CAS Number:
Molecular Weight:
168.36
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

type

Grade I

Quality Level

assay

≥99.0%

form

powder

mp

645 °C (lit.)

absorption

≤0.2 at 280 in H2O at 50%

application(s)

hematology
histology

SMILES string

[Cl-].[Cs+]

InChI

1S/ClH.Cs/h1H;/q;+1/p-1

InChI key

AIYUHDOJVYHVIT-UHFFFAOYSA-M

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This Item
C6914C3309C4036
Cesium chloride Grade I, ≥99.0%

C3011

Cesium chloride

Cesium chloride Grade II, ≥98%

C6914

Cesium chloride

Cesium chloride BioXtra, ≥99.5% (titration)

C3309

Cesium chloride

Cesium chloride for molecular biology, ≥98%

C4036

Cesium chloride

assay

≥99.0%

assay

≥98%

assay

≥99.5% (titration)

assay

≥98%

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

mp

645 °C (lit.)

mp

645 °C (lit.)

mp

645 °C (lit.)

mp

645 °C (lit.)

type

Grade I

type

Grade II

type

-

type

-

absorption

≤0.2 at 280 in H2O at 50%

absorption

≤0.2 at 280 in H2O at 50%

absorption

≤0.03 at 260 in H2O at 3 M, ≤0.03 at 280 in H2O at 3 M

absorption

-

Application

Cesium chloride has been used as a component of pipette solution, to record mechanosensitive currents in dorsal root ganglia neurons. It has been used in patch clamping to study neurons in intact myenteric ganglia.
Used for the preparation of electrically conducting glasses.Used to make solutions for the separation of RNA from DNA by density gradient centrifugation.

Biochem/physiol Actions

Oral intake of cesium chloride is known to increase the pH in cancer cells. Mild toxicity of cesium chloride might cause hypotension, gastrointestinal distress, numbness and syncope. It also leads to severe hypokalemia, hypomagnesemia, acute heart attack and polymorphic ventricular tachycardia in episodes.

Quality

Solutions may contain a slight haze.

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Patch clamp recording from enteric neurons in situ
Nancy O, et al.
Nature Protocols, 6(1), 15-15 (2011)
Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator
Jizhe H, et al.
Nature Protocols, 6(7), 979-979 (2011)
Petr Melnikov et al.
Biological trace element research, 135(1-3), 1-9 (2009-08-06)
The knowledge about cesium metabolism and toxicity is sparse. Oral intake of cesium chloride has been widely promoted on the basis of the hypothesis referred to as "high pH cancer therapy", a complimentary alternative medicine method for cancer treatment. However
Philippe Jean et al.
Nature communications, 11(1), 3208-3208 (2020-06-27)
Inner hair cells (IHCs) are the primary receptors for hearing. They are housed in the cochlea and convey sound information to the brain via synapses with the auditory nerve. IHCs have been thought to be electrically and metabolically independent from
Tuan A Ho et al.
Langmuir : the ACS journal of surfaces and colloids, 28(2), 1256-1266 (2011-12-14)
All-atom molecular dynamics simulations were conducted to study the dynamics of aqueous electrolyte solutions confined in slit-shaped silica nanopores of various degrees of protonation. Five degrees of protonation were prepared by randomly removing surface hydrogen atoms from fully protonated crystalline

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