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C6241

Sigma-Aldrich

Charcoal, Dextran Coated

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Synonym(s):
Dextran coated charcoal
EC Number:
231-153-3
NACRES:
NC.07

form

powder

Quality Level

200

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This Item
52194T116242874
Charcoal, Dextran Coated

Sigma-Aldrich

C6241

Charcoal, Dextran Coated

Sigma-Aldrich

Sigma-Aldrich

52194

Tetramethylrhodamine isothiocyanate–Dextran

Sigma-Aldrich

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T1162

Tetramethylrhodamine isothiocyanate–Dextran

Sigma-Aldrich

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42874

Tetramethylrhodamine isothiocyanate–Dextran

General description

Charcoal, Dextran Coated is made from acid washed charcoal powder and dextran, molecular weight 64-76kDa, combined in a 10:1 (w/w) ratio.

Application

Charcoal, Dextran Coated has been used:
  • as a supplement in cell culture media to test the functioning of androgen receptor
  • in the procedure of melatonin radioimmunoassay
  • for the preparation of steroid-free human serum
  • to reduce the creatinine level in untreated serum.

Biochem/physiol Actions

The use of dextran-coated charcoal makes the immunoassay of insulin in biological fluids simpler and more rapid. In theory, the charcoal coated with dextran will adsorb the free hormone and leave hormones that are bound to a carrier (or antibody). Dextran coated charcoal is used to strip hormones from serum instead of charcoal alone, because there is less loss of protein using dextran coated charcoal.

Other Notes

Dry preparation of dextran-treated charcoal

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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T1503
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25G
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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Modern Methods of Steroid Analysis (2012)
Coated charcoal immunoassay of insulin.
Herbert V
The Journal of Clinical Endocrinology and Metabolism, 25, 1375-1384 (1965)
Pineal oscillator functioning in the chicken--effect of photoperiod and melatonin.
Turkowska E
Chronobiology International, 31, 134-134 (2014)
Liang Shi et al.
Cell death & disease, 8(11), e3171-e3171 (2017-11-17)
Hepatocellular carcinoma (HCC) is a heterogeneous malignancy as a result of complex genetic and epigenetic alterations. HCC is characterized by a clear gender disparity for which there is lack of a clear mechanistic understanding. Androgen receptor (AR) is thought to
Shih-Hsing Leir et al.
Cell and tissue research, 381(2), 327-336 (2020-05-08)
Organoid cultures derived from primary human tissues facilitate the study of disease processes and the development of new therapeutics. Most men with cystic fibrosis (CF) are infertile due to defects in the epididymis and vas deferens; however, the causative mechanisms
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