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E5391

Sigma-Aldrich

Ethylenediaminetetraacetic acid tetrasodium salt hydrate

≥99.0%

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Synonym(s):
EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate
Linear Formula:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O
CAS Number:
Molecular Weight:
380.17 (anhydrous basis)
Beilstein/REAXYS Number:
3861753
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.83

biological source

synthetic (organic)

Quality Level

assay

≥99.0%

form

powder

technique(s)

ligand binding assay: suitable

impurities

Insoluble matter, passes filter test

pH

11.0-12.0 (0.1 M in H2O)

solubility

H2O: 0.1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.01%

cation traces

Al: ≤0.001%
As: ≤0.0001%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: <0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.06 at 280 in H2O at 0.1 M
≤1.5 at 260 in H2O at 0.1 M

application(s)

sample preparation

storage temp.

room temp

SMILES string

O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4

InChI key

GXFFSKMBMYHTAE-UHFFFAOYSA-J

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1 of 4

This Item
E2629003701ED4S
Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

-

form

powder

form

-

form

powder

form

powder

impurities

Insoluble matter, passes filter test

impurities

-

impurities

-

impurities

-

anion traces

chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.01%

anion traces

-

anion traces

-

anion traces

-

pH

11.0-12.0 (0.1 M in H2O)

pH

-

pH

-

pH

-

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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