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Sigma-Aldrich

Osteo-Bed Bone Embedding Kit

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NACRES:
NA.47

Quality Level

application(s)

hematology
histology

storage temp.

room temp

Application

Suitable for use with large and small mineralized (undecalcified) bone sections. Yields clear, hard blocks for cutting sections. Not water-soluble.

Recommended products

Osteo-Bed Bone Embedding Solvent (O8639) is available to remove plastic from sections.

Kit Components Only

Product No.
Description

  • Osteo-Bed Bone Embedding Resin A (O8514) 900 mL

  • Osteo-Bed Bone Embedding Catalyst (O8764) 2 x 12

recommended

Product No.
Description
Pricing

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Flam. Liq. 2 - Org. Perox. D - Repr. 1B - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

flash_point_f

50.0 °F

flash_point_c

10 °C


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Lei Qin et al.
Journal of orthopaedic translation, 34, 60-72 (2022-05-27)
The key focal adhesion protein β1 integrin plays an essential role in early skeletal development. However, roles of β1 integrin expression in osteocytes during the regulation of bone homeostasis and mechanotransduction are incompletely understood. To study the in vivo function
Nur-Vaizura Mohamad et al.
International journal of medical sciences, 18(16), 3665-3673 (2021-11-19)
Menopause is the leading cause of osteoporosis for elderly women due to imbalanced bone remodelling in the absence of oestrogen. The ability of tocotrienol in reversing established bone loss due to oestrogen deficiency remains unclear despite the plenitude of evidence
Colin K Yee et al.
Clinical & experimental metastasis, 25(8), 903-911 (2008-09-25)
In the current study, we examine heparin's anti-metastatic properties by using a well-defined mouse model of osteolytic bone metastasis. C57BL/6 mice were treated with increasing doses of unfractionated heparin (15, 20, or 25 units/mouse) 30 min prior to the left
Lei Qin et al.
Communications biology, 4(1), 402-402 (2021-03-27)
Osteocytes act as mechanosensors in bone; however, the underlying mechanism remains poorly understood. Here we report that deleting Kindlin-2 in osteocytes causes severe osteopenia and mechanical property defects in weight-bearing long bones, but not in non-weight-bearing calvariae. Kindlin-2 loss in
Yishu Wang et al.
JCI insight, 4(22) (2019-11-15)
Mammalian focal adhesion proteins Pinch1 and Pinch2 regulate integrin activation and cell-extracellular matrix adhesion and migration. Here, we show that deleting Pinch1 in osteocytes and mature osteoblasts using the 10-kb mouse Dmp1-Cre and Pinch2 globally (double KO; dKO) results in

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