F8649
Formate Dehydrogenase from Candida boidinii
lyophilized powder, 5.0-15.0 units/mg protein
Synonym(s):
FDH, Formate:NAD+ oxidoreductase
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About This Item
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biological source
fungus (Candida boidinii)
Quality Level
form
lyophilized powder
specific activity
5.0-15.0 units/mg protein
composition
Protein, 5.0-20.0% biuret
storage temp.
2-8°C
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Application
Formate Dehydrogenase (FDH) is used for diagnostics in large scale industrial processes. Its used in the production of an unnatural amino acid, tert-L-leucine, a component of some HIV protease and matrix metalloprotease inhibitors.
Biochem/physiol Actions
Formate dehydrogenase is an abundant enzyme from yeast Candida boidinii (CbFDH) that plays an important role in the energy supply of methylotrophic microorganisms and in the stress response of plants.
Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH.
Unit Definition
One unit will oxidize 1.0 μmole of formate to CO2 per min in the presence of β-NAD at pH 7.6 at 37 °C.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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