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Ginseng root from Panax quinquefolium (American ginseng)

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biological source

Panax quinquefolium



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General description

Ginseng comprises of saponins called ginsenosides, acidic polysaccharides and polyphenolic compounds.
Ginseng is an important herbal remedy extensively used to improve cardiac health and circulation. Treatment with Panax ginseng has shown to improve cardiac performance. It also increases protection against myocardial ischemia/reperfusion damage by enhancing nitric oxide (NO) release.


American ginseng (Panax quinquefolium) was used to test its protective effects against mitomycin C induced micronuclei in mice. It is used to test the adaptogenic and anti-amnesic properties of evolvulus alsinoides in rodents.
Ginseng root from Panax quinquefolium (American ginseng) has been used as control in hyperlocomotor activity studies and adaptogenic activity screening in mice.

Biochem/physiol Actions

Ginseng is an effective immune modulator and improves phagocytic functionality of macrophages and stimulates natural killer cells. Ginseng elicits anticancer and anti-diabetic functionality. Ginseng may provide protection in neurodegenerative diseases like Parkinson′s disease and Alzheimer′s disease. Ginseng improves liver regeneration and is effective in treating hepatocellular carcinoma.


Crude powder


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Hazard Statements

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Prasoon Gupta et al.
Chemical & pharmaceutical bulletin, 55(5), 771-775 (2007-05-03)
Bioactivity-guided purification of n-BuOH soluble fraction from the ethanol extract of Evolvulus alsinoides resulted in the isolation of two new compounds, 2,3,4-trihydroxy-3-methylbutyl 3-[3-hydroxy-4-(2,3,4-trihydroxy-2-methylbutoxy)-phenyl]-2-propenoate (1) and 1,3-di-O-caffeoyl quinic acid methyl ester (2) along with six known compounds, caffeic acid (3), 6-methoxy-7-O-beta-glucopyranoside
Ginseng: a dietary supplement as immune-modulator in various diseases
Riaz M, et al.
Trends in Food Science & Technology (2018)
Adaptogenic-active components from Kaempferia parviflora rhizomes
Pripdeevech P, et al.
Food Chemistry, 132(3), 1150-1155 (2012)
G N Masagatani et al.
The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 40(2), 83-88 (1986-02-01)
Current predicaments that academic educators deal with, that is, the conflicts between teaching and research responsibilities, the competition within universities for promotion and tenure, and the importance of viewing the university as a complex social-political system are addressed. Recommendations for
Effects of Panax ginseng in neurodegenerative diseases
Cho, Ik-Hyun
Journal of ginseng research, 36(4), 342-342 (2012)


HPLC Separation of Ginsenosides from American Ginseng

The HPLC method for ginsenoside separation was optimized using a ginsenoside standard mixture and then applied to a sample of American Ginseng root. The experimental conditions and chromatograms are shown.

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