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G7253

Sigma-Aldrich

Ginseng root from Panax quinquefolium (American ginseng)

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.81

biological source

Panax quinquefolium

form

powder

General description

Ginseng comprises of saponins called ginsenosides, acidic polysaccharides and polyphenolic compounds.
Ginseng is an important herbal remedy extensively used to improve cardiac health and circulation. Treatment with Panax ginseng has shown to improve cardiac performance. It also increases protection against myocardial ischemia/reperfusion damage by enhancing nitric oxide (NO) release.

Application

American ginseng (Panax quinquefolium) was used to test its protective effects against mitomycin C induced micronuclei in mice. It is used to test the adaptogenic and anti-amnesic properties of evolvulus alsinoides in rodents.
Ginseng root from Panax quinquefolium (American ginseng) has been used as control in hyperlocomotor activity studies and adaptogenic activity screening in mice.

Biochem/physiol Actions

Ginseng is an effective immune modulator and improves phagocytic functionality of macrophages and stimulates natural killer cells. Ginseng elicits anticancer and anti-diabetic functionality. Ginseng may provide protection in neurodegenerative diseases like Parkinson′s disease and Alzheimer′s disease. Ginseng improves liver regeneration and is effective in treating hepatocellular carcinoma.

Quality

Crude powder

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
061K1145V
061K1145
081H0043

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G N Masagatani et al.
The American journal of occupational therapy : official publication of the American Occupational Therapy Association, 40(2), 83-88 (1986-02-01)
Current predicaments that academic educators deal with, that is, the conflicts between teaching and research responsibilities, the competition within universities for promotion and tenure, and the importance of viewing the university as a complex social-political system are addressed. Recommendations for
Effects of Panax ginseng in neurodegenerative diseases
Cho, Ik-Hyun
Journal of ginseng research, 36(4), 342-342 (2012)
Ginseng: a dietary supplement as immune-modulator in various diseases
Riaz M, et al.
Trends in Food Science & Technology (2018)
Prasoon Gupta et al.
Chemical & pharmaceutical bulletin, 55(5), 771-775 (2007-05-03)
Bioactivity-guided purification of n-BuOH soluble fraction from the ethanol extract of Evolvulus alsinoides resulted in the isolation of two new compounds, 2,3,4-trihydroxy-3-methylbutyl 3-[3-hydroxy-4-(2,3,4-trihydroxy-2-methylbutoxy)-phenyl]-2-propenoate (1) and 1,3-di-O-caffeoyl quinic acid methyl ester (2) along with six known compounds, caffeic acid (3), 6-methoxy-7-O-beta-glucopyranoside
Adaptogenic-active components from Kaempferia parviflora rhizomes
Pripdeevech P, et al.
Food Chemistry, 132(3), 1150-1155 (2012)
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Articles

HPLC Separation: Ginsenosides from American Ginseng

Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.

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