Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

GS38

Sigma-Aldrich

GST T1-1, Recombinant Rat

Synonym(s):

AI255817: glutathione S-transferase, glutathione S-transferase, theta 1, Gstt1-1

Sign Into View Organizational & Contract Pricing

Select a Size

100 μG
$413.00

$413.00


Availability

Estimated to ship onMarch 06, 2025


Request a Bulk Order

Select a Size

Change View
100 μG
$413.00

About This Item

UNSPSC Code:
12352200
NACRES:
NA.26

$413.00


Availability

Estimated to ship onMarch 06, 2025


Request a Bulk Order

biological source

rat

Quality Level

recombinant

expressed in E. coli

assay

>95% (SDS-PAGE)

form

frozen liquid

specific activity

86.6

mol wt

25 kDa

concentration

1.22 mg/mL

storage temp.

−70°C

Gene Information

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
GS39GS60GS75
assay

>95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

biological source

rat

biological source

rat

biological source

human

biological source

human

concentration

1.22 mg/mL

concentration

2.44 mg/mL

concentration

2.0 mg/mL

concentration

1.98 mg/mL

form

frozen liquid

form

frozen liquid

form

frozen liquid

form

frozen liquid

mol wt

25 kDa

mol wt

23 kDa

mol wt

23 kDa

mol wt

26 kDa

General description

using spectrophotometric determination of 1,2-epoxy-3(4-nitrophenoxy)propane (ENPP) conjugation with reduced glutathione (5 mM) in 100 mM NaPO4 (pH 6.5) at room temperature.

Biochem/physiol Actions

Glutathione S-transferase theta 1 (Gstt1) is an enzyme that in rats is encoded by the Gstt1 gene. Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The GSTs are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Storage and Stability

The enzyme should be used by the end-user customer within 1 year of receipt.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


  • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

    Need A Sample COA?

    This is a sample Certificate of Analysis (COA) and may not represent a recently manufactured lot of this specific product.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Anna-Karin Larsson et al.
    Archives of biochemistry and biophysics, 497(1-2), 28-34 (2010-03-10)
    Glutathione transferase (GST) displaying enhanced activity with the cytostatic drug 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) and structurally related alkylating agents was obtained by molecular evolution. Mutant libraries created by recursive recombination of cDNA coding for human and rodent Theta-class GSTs were heterologously expressed

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service