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H2779

Sigma-Aldrich

HistoChoice® Clearing Agent

greener alternative
NACRES:
NA.47

form

liquid

Quality Level

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

color

colorless

density

0.760-0.820 g/mL

application(s)

hematology
histology

greener alternative category

storage temp.

room temp

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A7054A6929A0561
greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative product characteristics

-

greener alternative product characteristics

-

color

colorless

color

-

color

-

color

-

density

0.760-0.820 g/mL

density

-

density

-

density

-

application(s)

hematology
histology

application(s)

hematology
histology

application(s)

hematology
histology

application(s)

hematology
histology

greener alternative category

Aligned

greener alternative category

-

greener alternative category

-

greener alternative category

-

General description

HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites and nucleic acid sites. This formulation in non-citrus, contains no mercury, formaldehyde or glutaraldehyde.

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.

Application

HistoChoice® Clearing Agent is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.

Features and Benefits

  • Non-toxic and odorless
  • Preserves native antigenic and nucleic acid sites
  • Tissues retain original structure

Legal Information

HistoChoice is a registered trademark of Amresco, Inc.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

142.0 °F

Flash Point(C)

61.1 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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Uthpala Apekshani Jayawardena et al.
Environmental toxicology and chemistry, 36(10), 2855-2867 (2017-05-06)
Heavy metal contamination may have adverse effects on wetland biota, particularly on amphibians. Severe immunotoxic effects elicited in Euphlyctis hexadactylus (Indian green frog) because of metal exposure (Cd, Cr, Cu, Pb, and Zn) in the Bellanwila-Attidiya Sanctuary, a polluted urban
Bjarke Veierskov et al.
American journal of botany, 95(6), 766-771 (2008-06-01)
Meristematic activity in the bud meristem of Abies nordmanniana was visualized by ubiquitin immunohistochemical localization from before bud break and throughout shoot expansion. Ubiquitin was detected in meristematic cells either in the cytosol or nucleus, or both, depending on tissue
Anita S Patel et al.
The Journal of investigative dermatology, 128(12), 2888-2893 (2008-06-13)
An increasing number of studies report that genus beta human papillomaviruses (HPVs) are associated with skin cancer, with suggestions of specificity for squamous cell carcinoma (SCC) of the skin. We have conducted a systematic examination of HPV DNA in tumors
Janine A Duckworth et al.
Reproduction (Cambridge, England), 133(1), 177-186 (2007-01-25)
In a previous study, three infertility-relevant epitopes of possum ZP2 (Pep12 (amino acids 111-125), Pep31 (amino acids 301-315), and Pep44 (amino acids 431-445)) were identified using sera from possums (Trichosurus vulpecula) immunized with recombinant possum zona pellucida 2 (ZP2) constructs
Alexander Kunz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(7), 1649-1658 (2008-02-15)
CD36, a class-B scavenger receptor involved in multiple functions, including inflammatory signaling, may also contribute to ischemic brain injury through yet unidentified mechanisms. We investigated whether CD36 participates in the molecular events underlying the inflammatory reaction that accompanies cerebral ischemia

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