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I141

Sigma-Aldrich

Intralipid

20%, emulsion

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Synonym(s):
Phospholipid stabilized soybean oil
CAS Number:
MDL number:
NACRES:
NA.77

form

emulsion

Quality Level

concentration

20%

color

white

storage temp.

2-8°C

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This Item
PHR2882L13951545067
vibrant-m

I141

Intralipid

vibrant-m

PHR2882

Soybean Oil

vibrant-m

L1395

Lectin from Glycine max (soybean)

vibrant-m

1545067

Plastic additive 15

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

-

color

white

color

-

color

-

color

-

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

2-8°C

storage temp.

2-8°C

concentration

20%

concentration

-

concentration

-

concentration

-

Application

Intralipid has been used:
  • for testing its optical properties to be used as scattering medium for tissue phantom generation
  • as a component of agarose gel phantom to reduce scatter coefficients and background absorption
  • in infusion into mice in hyperinsulinemic-euglycemic clamps studies to evaluate its effect on nonesterified free fatty acids (NEFA) circulation

Biochem/physiol Actions

Intralipid is a lipid emulsion comprising soybean oil. It favors proinflammatory cytokines production and is recommended for the treatment of immune-mediated pregnancy and implantation failure. In parenteral nutrition, intralipid is the source of fats. It elicits protection in heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. Intralipid is an effective alternative for intravenous immunoglobulin and improves bioavailability of platinum based anti-cancer drugs.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Birgitta I Zielbauer et al.
Journal of colloid and interface science, 529, 197-204 (2018-06-13)
Oleosomes are stabilized by a complex outer phospholipid-protein-layer. To improve understanding of its structure and stabilization mechanism, this shell has to be studied in extracellular native conditions. This should be possible by SANS using contrast variation. Oleosomes are expected to
Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A
Li J, et al.
Anesthesiology, 117(4), 836-846 (2012)
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice
Xu W, et al.
Molecular and Cellular Endocrinology, 482(22), 1-10 (2019)
Lisa R Beutler et al.
eLife, 9 (2020-07-29)
Body weight is regulated by interoceptive neural circuits that track energy need, but how the activity of these circuits is altered in obesity remains poorly understood. Here we describe the in vivo dynamics of hunger-promoting AgRP neurons during the development
Benedict Mc Larney et al.
Journal of biophotonics, 12(6), e201800387-e201800387 (2019-02-01)
Accurate image reconstruction in volumetric optoacoustic tomography implies the efficient generation and collection of ultrasound signals around the imaged object. Non-uniform delivery of the excitation light is a common problem in optoacoustic imaging often leading to a diminished field of

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