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I4381

Sigma-Aldrich

IgG from porcine serum

reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

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Synonym(s):
Pig IgG
MDL number:
NACRES:
NA.46

conjugate

unconjugated

grade

reagent grade

Assay

≥95% (SDS-PAGE)

form

essentially salt-free, lyophilized powder

technique(s)

ELISA: suitable

storage temp.

2-8°C

target post-translational modification

unmodified

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IgG from rat serum reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

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IgG from bovine serum reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

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I5506

IgG from bovine serum

form

essentially salt-free, lyophilized powder

form

lyophilized powder

form

essentially salt-free, lyophilized powder

form

essentially salt-free, lyophilized powder

technique(s)

ELISA: suitable

technique(s)

-

technique(s)

-

technique(s)

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

grade

reagent grade

grade

reagent grade

grade

reagent grade

grade

reagent grade

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG from porcine serum specifically recognizes IgG from pig. Pig IgG is purified from normal pig serum by fractionation and ion-exchange chromatography. Immunoglobulin G (IgG) is part of the immunoglobulin family. The primary structure of this antibody contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains.

Application

IgG from porcine serum may be used in quantitative ELISA, a concentration of 0.5 μg/ml may be used as standard. Concentrations ranging from 3.9 to 250 ng/ml were used as standards in immune response measurements. Pig IgG was also used as standard in surface plasmon resonance phase imaging studies.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Simone Ladel et al.
Pharmaceutics, 10(3) (2018-07-28)
The use of therapeutic antibodies for the treatment of neurological diseases is of increasing interest. Nose-to-brain drug delivery is one strategy to bypass the blood brain barrier. The neonatal Fc receptor (FcRn) plays an important role in transepithelial transcytosis of
Kelly A Rich et al.
Gene therapy, 29(9), 513-519 (2021-11-23)
Numerous pediatric neurogenetic diseases may be optimally treated by in utero gene therapy (IUGT); but advancing such treatments requires animal models that recapitulate developmental physiology relevant to humans. One disease that could benefit from IUGT is the autosomal recessive motor
E van Heugten et al.
Journal of animal science, 72(3), 658-664 (1994-03-01)
To investigate the effect of aflatoxin (AF) and dietary methionine (MET) on immune responses of swine, a total of 288 pigs weaned at 21 d of age were allotted to 12 dietary treatments arranged in a 3 x 4 factorial
Kuo-Hoong Lee et al.
Biosensors & bioelectronics, 23(4), 466-472 (2007-07-10)
This study reports a microfluidic chip integrated with an arrayed immunoassay for surface plasmon resonance (SPR) phase imaging of specific bio-samples. The SPR phase imaging system uses a surface-sensitive optical technique to detect two-dimensional (2D) spatial phase variation caused by
Michael Bailey et al.
Clinical and diagnostic laboratory immunology, 11(2), 337-343 (2004-03-12)
Normal piglets weaned onto soy- or egg-based diets generated antibody responses to fed protein. Concurrent infection with transmissible gastroenteritis virus (TGEV) did not affect the responses to dietary antigens at weaning, nor did it affect the subsequent development of tolerance.

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