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I8885

Sigma-Aldrich

Anti-Human IgG (Fc specific) antibody produced in goat

whole antiserum

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MDL number:
NACRES:
NA.46

biological source

goat

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

secondary antibodies

clone

polyclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:50,000
quantitative precipitin assay: 4.0-7.0 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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This Item
I1011I1136I1886
technique(s)

indirect ELISA: 1:50,000, quantitative precipitin assay: 4.0-7.0 mg/mL

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:40,000, quantitative precipitin assay: 4.0 mg/mL

technique(s)

indirect ELISA: 1:10,000, quantitative precipitin assay: 3.0 mg/mL

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

goat

biological source

goat

biological source

goat

biological source

goat

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

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General description

Immunoglobulin G (IgG), a widely expressed serum antibody, has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein, usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. About 70 % of the total immunoglobulin consists of IgG.

Specificity

Specificity for the Fc fragment of human IgG is determined by immunoelectrophoresis (IEP) versus normal human serum and Fc fragment of human IgG. No reactivity is observed versus purified human IgA, IgG (Fab fragment), IgM, Bence Jones kappa and Bence Jones lambda myeloma proteins.

Application

Anti-Human IgG (Fc specific) antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA).

Biochem/physiol Actions

Immunoglobulin G (IgG) mainly helps in immune defense. It participates in hypersensitivity type II and type III. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Physical form

Goat Anti-Human IgG is supplied as a liquid containing 0.1% sodium azide (see MSDS) as a preservative.

Storage and Stability

For continuous use, store at 2-8°C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. This goat antiserum was maintained at pH 5.0 for 40 minutes to meet U.S.D.A. requirements.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1


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