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K3250

Sigma-Aldrich

Kynuramine dihydrobromide

monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline

Synonym(s):

3-(2-Aminophenyl)-3-oxopropanamine

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About This Item

Empirical Formula (Hill Notation):
C9H12N2O · 2HBr
CAS Number:
304-47-2
Molecular Weight:
326.03
MDL number:
MFCD00050683
UNSPSC Code:
12352204
PubChem Substance ID:
24896227
NACRES:
NA.32

product name

Kynuramine dihydrobromide, crystalline

assay

≥97% (TLC)

Quality Level

100

form

crystalline

solubility

water: 50 mg/mL, clear to slightly hazy

storage temp.

−20°C

SMILES string

Br.NCCC(=O)c1ccccc1N

InChI

1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H

InChI key

YUPVVZSYBUIDQR-UHFFFAOYSA-N

Application

Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase.

Biochem/physiol Actions

Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm.

Substrates

Substrate for monoamine oxidase

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
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