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L1026

Sigma-Aldrich

Lidocaine

analytical standard

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Synonym(s):
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine
Empirical Formula (Hill Notation):
C14H22N2O
CAS Number:
Molecular Weight:
234.34
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

grade

analytical standard

Quality Level

form

solid

packaging

vial of 200 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

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This Item
PHR1034L7757L0595000
Lidocaine analytical standard

L1026

Lidocaine

Lidocaine Pharmaceutical Secondary Standard; Certified Reference Material

PHR1034

Lidocaine

Lidocaine powder

L7757

Lidocaine

Lidocaine European Pharmacopoeia (EP) Reference Standard

L0595000

Lidocaine

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

200

Quality Level

300

Quality Level

100

Quality Level

-

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

pharmaceutical primary standard

packaging

vial of 200 mg

packaging

-

packaging

-

packaging

-

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

General description

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

Application

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

Biochem/physiol Actions

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

Packaging

Supplied in amber screw-cap vials

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Lidocaine hydrochloride British Pharmacopoeia (BP) Reference Standard

BP214

Lidocaine hydrochloride

Lidocaine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1257

Lidocaine hydrochloride

USP

USP

1560990

Prilocaine

MEGX ≥95% (HPLC)

Sigma-Aldrich

SML0087

MEGX

Use of within-group designs to test anti-tussive drugs in conscious guinea-pigs
Venkatasamy R, et al.
Journal of Pharmacological and Toxicological Methods, 61(2), 157-162 (2010)
Pharmacological approaches that slow lymphatic flow as a snakebite first aid
van Helden DF, et al.
PLoS Neglected Tropical Diseases, 8(2), e2722-e2722 (2014)
Key Issues in Plastic and Cosmetic Surgery (1999)
Seizures in Critical Care: A Guide to Diagnosis and Therapeutics (2008)
Effect of lidocaine on ventricular arrhythmias in patients with coronary heart disease
Gianelly R, et al.
The New England Journal of Medicine, 277(23), 1215-1219 (1967)

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