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L4754

Sigma-Aldrich

3-sn-Lysophosphatidylethanolamine from egg yolk

Type I, ≥99%

Synonym(s):

1-Acyl-sn-glycero-3-phospho(2-aminoethanol), L-α-Lysocephalin, L-α-Lysophosphatidylethanolamine

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About This Item

MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25

biological source

egg yolk

type

Type I

assay

≥99%

form

powder

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

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General description

Lysophosphatidylethanolamine (LysoPE), a prominent part of lysophospholipid, is obtained by the partial hydrolysis of phosphatidylethanolamine.

Application

3-sn-Lysophosphatidylethanolamine from egg yolk has been used:
  • to prepare liposomes for liposome binding and vesiculation assay
  • as a phospholipid standard in high-performance thin layer chromatography (HPTLC) to detect the phospholipid composition of platelet-derived microparticles
  • as a phospholipid standard in thin layer chromatography (TLC) to identify phospholipid in parasitophorous vacuoles (PV) containing Leishmania amazonensis

Biochem/physiol Actions

L-α-Lysophosphatidylethanolamines from egg yolk are enriched with stearate and palmitate acylated fatty acids.
Lysophosphatidylethanolamine (LPE) participates in the physiological and pathological processes of the nervous system. It plays a key role in the function of the cell membrane, apoptosis, oxidative stress, and inflammatory responses.

Quality

Contains primarily stearic and palmitic acids.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yuan-Yuan Zhao et al.
Journal of chromatography. A, 1218(32), 5470-5479 (2011-07-09)
A hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC LC-MS/MS) method using multiple scan modes was developed to separate and quantify 11 compounds and lipid classes including acetylcholine (AcCho), betaine (Bet), choline (Cho), glycerophosphocholine (GPC), lysophosphatidylcholine (LPC), lysophosphatidylethanolamine (LPE), phosphatidylcholine (PC)
Nguyen Dang Hung et al.
Lipids, 46(10), 893-906 (2011-07-12)
In the present study, the anti-inflammatory action of lysophosphatidylethanolamine (lysoPtdEtn), orally administered, in zymosan A-induced peritonitis was examined. Oral administration of 2-DHA-lysoPtdEtn (ED(50), ~111 μg/kg) or 2-ARA-lysoPtdEtn (ED(50), 221 μg/kg) was found to inhibit the plasma leakage in mice treated with zymosan
E Biró et al.
Journal of thrombosis and haemostasis : JTH, 3(12), 2754-2763 (2005-12-20)
The processes that govern the distribution of molecules between platelets and the microparticles (MP) they release are unknown. Certain proteins are sorted selectively into MP, but lipid sorting has not been studied. To compare the phospholipid composition and cholesterol content
C Henriques et al.
Parasitology research, 89(2), 123-133 (2002-12-19)
One fundamental step of Leishmania-macrophage interaction is the phase of parasite internalization through an endocytic process, with the formation of the parasitophorous vacuole (PV). The present study analyzed this process using two approaches. First, to investigate the host cell proteins
Kumiko Makide et al.
Prostaglandins & other lipid mediators, 89(3-4), 135-139 (2009-05-12)
It is now widely accepted that lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G-protein-coupled receptors. Notably, recent studies of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have revealed their essential roles in vivo. On

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